Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LATS1 | O95835 | 2/20 | 0.45 |
| ▸ | PRKCA | P17252 | 5/20 | 0.43 |
| ▸ | PRKCD | Q05655 | 5/20 | 0.43 |
| ▸ | PRKCB | P05771 | 4/20 | 0.43 |
| ▸ | PRKCH | P24723 | 4/20 | 0.43 |
| ▸ | PRKCE | Q02156 | 4/20 | 0.43 |
| ▸ | PRKCQ | Q04759 | 4/20 | 0.43 |
| ▸ | PRKD1 | Q15139 | 4/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | NCF1 | P14598 | 1/20 | 0.41 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.40 |
| ▸ | PRKCG | P05129 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | PRKACA | P17612 | 2/20 | 0.40 |
| ▸ | PRKACG | P22612 | 2/20 | 0.40 |
| ▸ | PRKACB | P22694 | 2/20 | 0.40 |
| ▸ | PRKCI | P41743 | 2/20 | 0.40 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL722215 | 0.80 | BACE1 (0.55) | NCF1KDM4ECYP1A2BACE1HTR1A | |
| Hydrochloric Acid SCHEMBL15066499 | 0.78 | BACE1 (0.54) | NCF1KDM4ECYP1A2BACE1HTR1A | |
| Hydrochloric Acid SCHEMBL5501060 | 0.77 | BACE1 (0.53) | NCF1KDM4ECYP1A2BACE1HTR1A | |
| SCHEMBL9229724 | 0.69 | HTR6 (0.48) | NCF1KDM4ECYP1A2BACE1SLC6A4 | |
| SCHEMBL20521379 | 0.69 | ADRB2 (0.52) | LATS1PRKCAPRKCQADRB2NCF1 | |
| SCHEMBL15066502 | 0.69 | RPS6KA3 (0.47) | ADRB2NCF1PLD1CHRNB2CHRNA4 | |
| SCHEMBL27476454 | 0.69 | HTR6 (0.47) | NCF1KDM4ECYP1A2BACE1SLC6A4 | |
| Hydrochloric Acid SCHEMBL29586065 | 0.68 | ADRB2 (0.50) | LATS1PRKCAPRKCQADRB2NCF1 | |
| SCHEMBL2420958 | 0.68 | CYP2D6 (0.66) | LATS1PRKCAPRKCDPRKCBPRKCH | |
| SCHEMBL1904695 | 0.67 | ADRB2 (0.59) | LATS1ADRB2NCF1PLD1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9371336-B2 | Compounds for treating spinal muscular atrophy | PTC THERAPEUTICS, INC. (US) | 2016-06-21 | — | — | US | disclosed |
| US-20150166575-A1 | COMPOUNDS FOR TREATING SPINAL MUSCULAR ATROPHY | PTC THERAPEUTICS INC. (US) | 2015-06-18 | — | — | US | disclosed |
| EP-2819519-A1 | COMPOUNDS FOR TREATING SPINAL MUSCULAR ATROPHY | PTC Therapeutics, Inc. (US) | 2015-01-07 | — | — | EP | disclosed |
| WO-2013130689-A1 | COMPOUNDS FOR TREATING SPINAL MUSCULAR ATROPHY | PTC THERAPEUTICS, INC. (US) | 2013-09-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150166575-A1 | COMPOUNDS FOR TREATING SPINAL MUSCULAR ATROPHY | SMN1; SMN2, CPT1B, GYS1 | LATS1 2742/4885PRKCA 870/4885PRKCD 2232/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.