Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.44 |
| ▸ | RPA1 | P27694 | 4/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | RXRG | P48443 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29397883 | 1.00 | MEN1 (0.45) | MEN1KMT2AMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL1765424 | 0.93 | MEN1 (0.44) | MEN1KMT2AMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL1764920 | 0.92 | MEN1 (0.43) | MEN1KMT2AMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL1765015 | 0.91 | MEN1 (0.50) | MEN1KMT2AMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL1765282 | 0.90 | MEN1 (0.42) | MEN1KMT2AMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL1764969 | 0.90 | PTGS2 (0.48) | MEN1KMT2AMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL1765351 | 0.90 | PPP1CA (0.46) | MEN1KMT2AMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL1765442 | 0.90 | KDM1A (0.45) | MEN1KMT2AMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL1764936 | 0.90 | RPA1 (0.44) | MEN1KMT2AMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL15004283 | 0.89 | MEN1 (0.44) | MEN1KMT2AMAPTSMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2295038-B1 | Solid dispersion comprising an anti-HIV agent | AICURIS GMBH & CO KG (DE) | 2013-05-29 | — | — | EP | disclosed |
| EP-2295038-B1 | Solid dispersion comprising an anti-HIV agent | AICURIS GMBH & CO KG (DE) | 2013-05-29 | — | — | EP | disclosed |
| US-20130072531-A1 | SOLID DISPERSION COMPRISING AN ANTI-HIV AGENT | AICURIS GMBH & CO. KG (DE) | 2013-03-21 | — | — | US | disclosed |
| US-20130072531-A1 | SOLID DISPERSION COMPRISING AN ANTI-HIV AGENT | AICURIS GMBH & CO. KG (DE) | 2013-03-21 | — | — | US | disclosed |
| US-20130072531-A1 | SOLID DISPERSION COMPRISING AN ANTI-HIV AGENT | AICURIS GMBH & CO. KG (DE) | 2013-03-21 | — | — | US | disclosed |
| US-8399682-B2 | Substituted (pyrazolylcarbonyl)imidazolidinones and their use | AICURIS GMBH & CO. KG (DE) | 2013-03-19 | — | — | US | disclosed |
| US-8399682-B2 | Substituted (pyrazolylcarbonyl)imidazolidinones and their use | AICURIS GMBH & CO. KG (DE) | 2013-03-19 | — | — | US | disclosed |
| US-8399682-B2 | Substituted (pyrazolylcarbonyl)imidazolidinones and their use | AICURIS GMBH & CO. KG (DE) | 2013-03-19 | — | — | US | disclosed |
| US-20110124618-A1 | SUBSTITUTED (PYRAZOLYLCARBONYL)IMIDAZOLIDINONES AND THEIR USE | AICURIS GMBH & CO. KG (DE) | 2011-05-26 | — | — | US | disclosed |
| US-20110124618-A1 | SUBSTITUTED (PYRAZOLYLCARBONYL)IMIDAZOLIDINONES AND THEIR USE | AICURIS GMBH & CO. KG (DE) | 2011-05-26 | — | — | US | disclosed |
| US-20110124618-A1 | SUBSTITUTED (PYRAZOLYLCARBONYL)IMIDAZOLIDINONES AND THEIR USE | AICURIS GMBH & CO. KG (DE) | 2011-05-26 | — | — | US | disclosed |
| WO-2011029909-A1 | SOLID DISPERSION COMPRISING AN ANTI-HIV AGENT | AICURIS GMBH & CO. KG (DE) | 2011-03-17 | — | — | WO | disclosed |
| WO-2011029909-A1 | SOLID DISPERSION COMPRISING AN ANTI-HIV AGENT | AICURIS GMBH & CO. KG (DE) | 2011-03-17 | — | — | WO | disclosed |
| EP-2295038-A1 | Solid dispersion comprising an anti-HIV agent | AiCuris GmbH & Co. KG (DE) | 2011-03-16 | — | — | EP | disclosed |
| EP-2295038-A1 | Solid dispersion comprising an anti-HIV agent | AiCuris GmbH & Co. KG (DE) | 2011-03-16 | — | — | EP | disclosed |
| WO-2009115213-A1 | (PYRAZOLYL CARBONYL)IMIDAZOLIDINONE DERIVATIVES FOR THE TREATMENT OF RETROVIRAL DISEASES | AICURIS GMBH & CO. KG (DE) | 2009-09-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110124618-A1 | SUBSTITUTED (PYRAZOLYLCARBONYL)IMIDAZOLIDINONES AND THEIR USE | TPMT, PAICS, THPO | MEN1 2360/4885KMT2A 1193/4885MAPT 2876/4885 |
| US-20130072531-A1 | SOLID DISPERSION COMPRISING AN ANTI-HIV AGENT | SORD, SUDS3, SUPT16H | MEN1 4763/4885KMT2A 2254/4885MAPT 58/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.