SCHEMBL1765351

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1765529	0.96	PPP1CA (0.47)	PPP1CAPTGS2PTGS1RXRARXRB
	SCHEMBL1765378	0.92	CCKAR (0.46)	PPP1CAPTGS2PTGS1MALT1CCKAR
	SCHEMBL12597373	0.90	KDM1A (0.43)	PPP1CAPTGS2PTGS1MALT1CCKAR
	SCHEMBL1765049	0.90	SLC5A1 (0.44)	PPP1CAPTGS2PTGS1MALT1CCKAR
	SCHEMBL1765402	0.90	PTGS2 (0.52)	PPP1CAPTGS2PTGS1MALT1CCKAR
	SCHEMBL14995519	0.90	MARS1 (0.45)	PTGS2PTGS1MALT1MGLLMEN1
	SCHEMBL1526038	0.90	MEN1 (0.45)	PPP1CAPTGS2PTGS1RXRARXRB
	SCHEMBL14995482	0.90	MALT1 (0.45)	PPP1CAPTGS2PTGS1RXRARXRB
	SCHEMBL1764979	0.89	CCKAR (0.51)	PPP1CAPTGS2PTGS1MALT1CCKAR
	SCHEMBL1764968	0.89	KDM1A (0.44)	PPP1CAPTGS2PTGS1MALT1CCKAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.