SCHEMBL15271480

SCHEMBL15271480

CC(=O)/C(C)=C/c1ccccc1O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.55
LMNA P02545 1/20 0.55
TRIM24 O15164 1/20 0.50
TRIM33 Q9UPN9 1/20 0.50
NFKB1 P19838 2/20 0.48
JUN P05412 1/20 0.48
NFE2L2 Q16236 1/20 0.48
CA2 P00918 2/20 0.47
CA1 P00915 1/20 0.47
CA4 P22748 1/20 0.47
CDK4 P11802 1/20 0.44
CCND1 P24385 1/20 0.44
CHRNA7 P36544 1/20 0.43
CTRC Q99895 1/20 0.43
DUSP3 P51452 1/20 0.43
PTPN5 P54829 1/20 0.43
PTPN11 Q06124 1/20 0.43
IAPP P10997 1/20 0.43
BCHE P06276 1/20 0.43
GUSB P08236 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15271482 1.00 MAPT (0.55) MAPTLMNATRIM24TRIM33NFKB1
SCHEMBL17122440 1.00 MAPT (0.55) MAPTLMNATRIM24TRIM33NFKB1
SCHEMBL208434 0.86 AKR1C3 (0.59) MAPTLMNATRIM24TRIM33NFKB1
SCHEMBL1137305 0.86 AKR1C3 (0.59) MAPTLMNATRIM24TRIM33NFKB1
SCHEMBL224822 0.84 MAPT (0.52) MAPTLMNATRIM24TRIM33NFKB1
SCHEMBL3865338 0.84 MAPT (0.52) MAPTLMNATRIM24TRIM33NFKB1
SCHEMBL4924447 0.83 MAPT (0.55) MAPTLMNATRIM24TRIM33NFKB1
SCHEMBL25142236 0.81 MAPT (0.49) MAPTLMNATRIM24TRIM33NFKB1
SCHEMBL11052877 0.81 MAPT (0.49) MAPTLMNATRIM24TRIM33NFKB1
Phenol SCHEMBL4607887 0.81 AKR1C3 (0.53) MAPTLMNATRIM24TRIM33NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2847318-A1 PESTICIDAL FLAVOBACTERIUM STRAIN AND BIOACTIVE COMPOSITIONS, METABOLITES AND USES Marrone Bio Innovations, Inc. (US) 2015-03-18 EP claimed
US-20150031534-A1 PESTICIDAL FLAVOBACTERIUM STRAIN AND BIOACTIVE COMPOSITIONS METABOLITES AND USES PRO FARM GROUP, INC. 2015-01-29 US claimed
WO-2013138398-A1 PESTICIDAL FLAVOBACTERIUM STRAIN AND BIOACTIVE COMPOSITIONS, METABOLITES AND USES MARRONE BIO INNOVATIONS, INC. (US) 2013-09-19 WO claimed
US-20210227833-A1 PESTICIDAL FLAVOBACTERIUM STRAIN AND BIOACTIVE COMPOSITIONS METABOLITES AND USES MARRONE BIO INNOVATIONS, INC. (US) 2021-07-29 US disclosed
US-20210227833-A1 PESTICIDAL FLAVOBACTERIUM STRAIN AND BIOACTIVE COMPOSITIONS METABOLITES AND USES MARRONE BIO INNOVATIONS, INC. (US) 2021-07-29 US disclosed
US-11013236-B2 Pesticidal Flavobacterium strain and bioactive compositions metabolites and uses MARRONE BIO INNOVATIONS, INC. (US) 2021-05-25 US disclosed
US-11013236-B2 Pesticidal Flavobacterium strain and bioactive compositions metabolites and uses MARRONE BIO INNOVATIONS, INC. (US) 2021-05-25 US disclosed
CN-107090414-B Pesticidal flavobacterium strains 马罗内生物创新公司 2020-12-04 CN disclosed
EP-2847318-B1 PESTICIDAL FLAVOBACTERIUM STRAIN AND BIOACTIVE COMPOSITIONS, METABOLITES AND USES MARRONE BIO INNOVATIONS INC (US) 2019-01-23 EP disclosed
EP-2847318-A1 PESTICIDAL FLAVOBACTERIUM STRAIN AND BIOACTIVE COMPOSITIONS, METABOLITES AND USES Marrone Bio Innovations, Inc. (US) 2015-03-18 EP disclosed
US-20150031534-A1 PESTICIDAL FLAVOBACTERIUM STRAIN AND BIOACTIVE COMPOSITIONS METABOLITES AND USES PRO FARM GROUP, INC. 2015-01-29 US disclosed
US-20150031534-A1 PESTICIDAL FLAVOBACTERIUM STRAIN AND BIOACTIVE COMPOSITIONS METABOLITES AND USES PRO FARM GROUP, INC. 2015-01-29 US disclosed
US-20150031534-A1 PESTICIDAL FLAVOBACTERIUM STRAIN AND BIOACTIVE COMPOSITIONS METABOLITES AND USES PRO FARM GROUP, INC. 2015-01-29 US disclosed
WO-2013138398-A1 PESTICIDAL FLAVOBACTERIUM STRAIN AND BIOACTIVE COMPOSITIONS, METABOLITES AND USES MARRONE BIO INNOVATIONS, INC. (US) 2013-09-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210227833-A1 PESTICIDAL FLAVOBACTERIUM STRAIN AND BIOACTIVE COMPOSITIONS METABOLITES AND USES BLVRB, PRDX6, ACHE MAPT 3804/4885LMNA 2685/4885TRIM24 4298/4885
US-20150031534-A1 PESTICIDAL FLAVOBACTERIUM STRAIN AND BIOACTIVE COMPOSITIONS METABOLITES AND USES BLVRB, PRDX6, ACHE MAPT 3804/4885LMNA 2685/4885TRIM24 4298/4885
US-11013236-B2 Pesticidal Flavobacterium strain and bioactive compositions metabolites and uses BLVRB, PRDX6, ACHE MAPT 3804/4885LMNA 2685/4885TRIM24 4298/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.