Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.30 |
| ▸ | THRA | P10827 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28713240 | 0.86 | PLA2G2A (0.36) | PLA2G2ATSHRNR5A1BLM | |
| SCHEMBL21523874 | 0.82 | RARB (0.40) | TSHRNR5A1 | |
| Hydrochloric Acid SCHEMBL27856205 | 0.80 | RARB (0.38) | TSHRNR5A1 | |
| Iodide SCHEMBL2313827 | 0.78 | PDE5A (0.38) | — | |
| SCHEMBL585095 | 0.78 | RARB (0.36) | TSHRNR5A1 | |
| SCHEMBL7867503 | 0.78 | MCHR1 (0.30) | — | |
| SCHEMBL7860936 | 0.78 | MCHR1 (0.30) | — | |
| SCHEMBL2202844 | 0.76 | TSHR (0.37) | TSHRNR5A1 | |
| SCHEMBL2226184 | 0.75 | CYP1A2 (0.32) | — | |
| SCHEMBL6847308 | 0.75 | PLA2G2A (0.34) | PLA2G2ABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150273457-A1 | HIGHLY ACTIVE MULTIDENTATE CATALYSTS FOR EFFICIENT ALKYNE METATHESIS | NATIONAL SCIENCE FOUNDATION | 2015-10-01 | — | — | US | disclosed |
| US-8993804-B2 | Highly active multidentate catalysts for efficient alkyne metathesis | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2015-03-31 | — | — | US | disclosed |
| US-20130261295-A1 | Highly Active Multidentate Catalysts for Efficient Alkyne Metathesis | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2013-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150273457-A1 | HIGHLY ACTIVE MULTIDENTATE CATALYSTS FOR EFFICIENT ALKYNE METATHESIS | PCNA, TRIM58, CAD | PLA2G2A 3799/4885TSHR 4815/4885NR5A1 4767/4885 |
| US-20130261295-A1 | Highly Active Multidentate Catalysts for Efficient Alkyne Metathesis | PCNA, TRIM58, CAD | PLA2G2A 3799/4885TSHR 4815/4885NR5A1 4767/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.