Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.57 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.57 |
| ▸ | MLNR | O43193 | 1/20 | 0.57 |
| ▸ | HTR2A | P28223 | 1/20 | 0.57 |
| ▸ | HTR2C | P28335 | 1/20 | 0.57 |
| ▸ | HRH1 | P35367 | 1/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.57 |
| ▸ | DRD3 | P35462 | 1/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.57 |
| ▸ | HTR2B | P41595 | 1/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28451511 | 0.89 | CYP3A4 (0.61) | CYP3A4CYP2D6CHRM2CHRM1CHRM3 | |
| SCHEMBL2488944 | 0.88 | LMNA (0.50) | CYP3A4CYP2D6CHRM2CHRM1CHRM3 | |
| SCHEMBL2443032 | 0.84 | CHRM2 (0.54) | CYP3A4CYP2D6CHRM2CHRM1CHRM3 | |
| SCHEMBL16732280 | 0.83 | LMNA (0.51) | CYP3A4CYP2D6CHRM2CHRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL4541197 | 0.82 | CHRM2 (0.52) | CYP3A4CYP2D6CHRM2CHRM1CHRM3 | |
| SCHEMBL28668236 | 0.82 | LMNA (0.55) | CYP3A4CYP2D6CHRM2CHRM1CHRM3 | |
| SCHEMBL29242015 | 0.81 | CHRM2 (0.50) | CYP3A4CYP2D6CHRM2CHRM1CHRM3 | |
| SCHEMBL5158545 | 0.81 | MEN1 (0.68) | CYP3A4CYP2D6CHRM2CHRM1CHRM3 | |
| SCHEMBL16732185 | 0.81 | LMNA (0.53) | CYP3A4CYP2D6CHRM2CHRM1CHRM3 | |
| SCHEMBL4561863 | 0.81 | CHRM2 (0.51) | CYP3A4CYP2D6CHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2470504-B1 | SYNTHESIS OF PROPIVERINE HYDROCHLORIDE | ANDAGAR RAMAKRISHNA RAMESHA (IN) | 2013-10-16 | — | — | EP | disclosed |
| EP-2470504-B1 | SYNTHESIS OF PROPIVERINE HYDROCHLORIDE | ANDAGAR RAMAKRISHNA RAMESHA (IN) | 2013-10-16 | — | — | EP | disclosed |