SCHEMBL28668236

SCHEMBL28668236

CCCOC(=O)C(C(=O)OCCC)(c1ccccc1)c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.55
ALDH1A1 P00352 2/20 0.52
CHRM2 P08172 6/20 0.50
CHRM1 P11229 6/20 0.50
CHRM3 P20309 6/20 0.50
SCN1A P35498 3/20 0.50
SCN2A Q99250 3/20 0.50
SCN3A Q9NY46 3/20 0.50
CYP3A4 P08684 3/20 0.50
CYP2D6 P10635 3/20 0.50
CHRM4 P08173 3/20 0.50
CYP1A2 P05177 2/20 0.50
CYP2C9 P11712 2/20 0.50
CYP2C19 P33261 2/20 0.50
CHRM5 P08912 1/20 0.50
TSHR P16473 1/20 0.50
NFKB1 P19838 1/20 0.50
MTOR P42345 1/20 0.50
RAB9A P51151 1/20 0.50
SIGMAR1 Q99720 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28004290 0.91 LMNA (0.46) LMNAALDH1A1CHRM2CHRM1CHRM3
SCHEMBL28558105 0.89 TSHR (0.54) LMNAALDH1A1CHRM2CHRM1CHRM3
SCHEMBL28658992 0.88 TSHR (0.56) LMNAALDH1A1CHRM2CHRM1CHRM3
SCHEMBL5639395 0.85 PIN1 (0.56) ALDH1A1CHRM2CHRM1CHRM3CHRM4
SCHEMBL5158545 0.84 MEN1 (0.68) LMNAALDH1A1CHRM2CHRM1CHRM3
SCHEMBL10623735 0.84 LMNA (0.53) LMNAALDH1A1CHRM2CHRM1CHRM3
SCHEMBL16732185 0.84 LMNA (0.53) LMNAALDH1A1CHRM2CHRM1CHRM3
SCHEMBL2417813 0.84 LMNA (0.53) LMNAALDH1A1CHRM2CHRM1CHRM3
SCHEMBL5810680 0.82 LMNA (0.51) LMNAALDH1A1CHRM2CHRM1CHRM3
SCHEMBL15310068 0.82 CYP3A4 (0.58) LMNAALDH1A1CHRM2CHRM1CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118909171-A Solid catalyst component for olefin polymerization reaction, preparation method and application thereof 中国石油化工股份有限公司 2024-11-08 CN claimed
CN-118909171-A Solid catalyst component for olefin polymerization reaction, preparation method and application thereof 中国石油化工股份有限公司 2024-11-08 CN disclosed
CN-109678996-B Catalyst component and catalyst system for olefin polymerization, prepolymerized catalyst system and olefin polymerization method 中国石油化工股份有限公司 2021-11-19 CN disclosed
CN-109678998-B Catalyst component and catalyst system for olefin polymerization, prepolymerized catalyst system and olefin polymerization method 中国石油化工股份有限公司 2021-11-19 CN disclosed
CN-109678997-B Catalyst component and catalyst for olefin polymerization, prepolymerized catalyst and olefin polymerization method 中国石油化工股份有限公司 2021-11-19 CN disclosed
CN-109679006-B Catalyst component and catalyst system for olefin polymerization, prepolymerized catalyst system and olefin polymerization method 中国石油化工股份有限公司 2021-08-03 CN disclosed
CN-109679004-B Catalyst component and catalyst system for olefin polymerization, prepolymerized catalyst system and olefin polymerization method 中国石油化工股份有限公司 2021-05-11 CN disclosed