Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 2/20 | 0.48 |
| ▸ | CYBB | P04839 | 3/20 | 0.47 |
| ▸ | NOX4 | Q9NPH5 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.39 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | GMNN | O75496 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3403001 | 1.00 | MDM2 (0.48) | MDM2CYBBNOX4NPC1MAPT | |
| SCHEMBL153105 | 0.85 | MDM2 (0.54) | MDM2CYBBNOX4NPC1MAPT | |
| SCHEMBL153106 | 0.85 | MDM2 (0.54) | MDM2CYBBNOX4NPC1MAPT | |
| SCHEMBL3402526 | 0.85 | MDM2 (0.48) | MDM2CYBBNOX4NPC1MAPT | |
| SCHEMBL3402528 | 0.85 | MDM2 (0.48) | MDM2CYBBNOX4NPC1MAPT | |
| SCHEMBL14889480 | 0.72 | CYBB (0.41) | MDM2CYBBNOX4MAPTMAPK1 | |
| SCHEMBL3405296 | 0.72 | CYBB (0.41) | MDM2CYBBNOX4MAPTMAPK1 | |
| SCHEMBL3402877 | 0.71 | MDM2 (0.48) | MDM2CYBBNOX4MAPTMAPK1 | |
| SCHEMBL3402879 | 0.71 | MDM2 (0.48) | MDM2CYBBNOX4MAPTMAPK1 | |
| SCHEMBL10848654 | 0.70 | TYR (0.57) | MDM2NPC1MAPTMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427431-B1 | NOVEL INDICATOR PLATFORM | BIOSYNTH AG (CH) | 2013-05-01 | — | — | EP | disclosed |
| EP-2256103-A1 | Novel indicator platform | Biosynth AG (CH) | 2010-12-01 | — | — | EP | disclosed |