Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | FOS | P01100 | 1/20 | 0.56 |
| ▸ | TTR | P02766 | 1/20 | 0.56 |
| ▸ | JUN | P05412 | 1/20 | 0.56 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.56 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.56 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27870957 | 0.99 | CYP3A4 (0.59) | CYP3A4CYP2D6CYP2C9CYP2C19TSHR | |
| SCHEMBL18043458 | 0.94 | FOS (0.59) | CYP3A4CYP2D6CYP2C9CYP2C19TSHR | |
| SCHEMBL18043454 | 0.91 | FOS (0.59) | CYP3A4CYP2D6CYP2C9CYP2C19TSHR | |
| SCHEMBL5047574 | 0.90 | HTR1A (0.60) | CYP3A4CYP2D6CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL5051127 | 0.90 | HTR1A (0.60) | CYP3A4CYP2D6CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL22462684 | 0.90 | HTR1A (0.60) | CYP3A4CYP2D6CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL5047559 | 0.90 | HTR1A (0.60) | CYP3A4CYP2D6CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL28447253 | 0.86 | HTR1A (0.56) | CYP3A4CYP2D6CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL29291131 | 0.84 | FOS (0.57) | CYP3A4CYP2C9CYP2C19TSHRCYP1A2 | |
| SCHEMBL19127736 | 0.84 | MMP1 (0.58) | CYP3A4TSHRPOLBBLMNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1627634-B1 | Use of capsinoids for the treatment of arteriosclerosis | AJINOMOTO KK (JP) | 2013-10-16 | — | — | EP | claimed |