Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | EED | O75530 | 3/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | PLK4 | O00444 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5392020 | 0.82 | EGLN1 (0.35) | MAPTRAB9AALDH1A1NPC1L3MBTL1 | |
| SCHEMBL30102517 | 0.77 | TRPV1 (0.58) | MAPTALDH1A1LMNAKDM4EKMT2A | |
| SCHEMBL2723517 | 0.77 | TRPV1 (0.58) | MAPTALDH1A1LMNAKDM4EKMT2A | |
| SCHEMBL15310778 | 0.69 | TRPV1 (0.47) | TRPV1 | |
| SCHEMBL5732429 | 0.68 | ALDH1A1 (0.38) | ALDH1A1USP2HPGDHSD17B10KMT2A | |
| SCHEMBL17543074 | 0.68 | SLC2A1 (0.44) | MAPTRAB9AALDH1A1NPC1L3MBTL1 | |
| SCHEMBL15310795 | 0.68 | TRPV1 (0.44) | MAPTRAB9AKMT2ATRPV1MALT1 | |
| SCHEMBL15312400 | 0.68 | TRPV1 (0.63) | ALDH1A1HPGDTRPV1 | |
| SCHEMBL2690334 | 0.67 | NOS3 (0.36) | RAB9AALDH1A1NPC1LMNAEGLN1 | |
| SCHEMBL9030925 | 0.67 | ALDH1A1 (0.50) | MAPTRAB9AALDH1A1NPC1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130274271-A1 | METHODS AND COMPOSITIONS FOR PREVENTION AND TREATMENTOF CARDIAC HYPERTROPHY | UNIVERSITY OF HAWAII (US) | 2013-10-17 | — | — | US | claimed |
| US-20210069184-A1 | METHODS AND COMPOSITIONS FOR PREVENTION AND TREATMENT OF CARDIAC HYPERTROPHY | UNIV HAWAII (US) | 2021-03-11 | — | — | US | disclosed |