Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 13/20 | 0.87 |
| ▸ | PGR | P06401 | 6/20 | 0.87 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.87 |
| ▸ | AR | P10275 | 5/20 | 0.87 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.87 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.87 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.87 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.81 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.81 |
| ▸ | CNR1 | P21554 | 1/20 | 0.66 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.66 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | USP2 | O75604 | 2/20 | 0.61 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | MLNR | O43193 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cloticasone Propionate SCHEMBL14518229 | 1.00 | NR3C1 (0.87) | NR3C1PGRCYP3A4ARADORA3 | |
| Cloticasone Propionate SCHEMBL42706 | 1.00 | NR3C1 (0.87) | NR3C1PGRCYP3A4ARADORA3 | |
| Cloticasone Propionate SCHEMBL13773292 | 1.00 | NR3C1 (0.87) | NR3C1PGRCYP3A4ARADORA3 | |
| Cloticasone Propionate SCHEMBL1860078 | 1.00 | NR3C1 (0.87) | NR3C1PGRCYP3A4ARADORA3 | |
| Cloticasone Propionate SCHEMBL15311035 | 1.00 | NR3C1 (0.87) | NR3C1PGRCYP3A4ARADORA3 | |
| Cloticasone Propionate SCHEMBL17735459 | 1.00 | NR3C1 (0.87) | NR3C1PGRCYP3A4ARADORA3 | |
| SCHEMBL14479087 | 0.94 | NR3C1 (0.90) | NR3C1PGRCYP3A4ARADORA3 | |
| SCHEMBL195423 | 0.94 | NR3C1 (0.90) | NR3C1PGRCYP3A4ARADORA3 | |
| Fluticasone Propionate SCHEMBL14339613 | 0.93 | NR3C1 (1.00) | NR3C1PGRCYP3A4ARADORA3 | |
| Fluticasone Propionate SCHEMBL5482829 | 0.93 | NR3C1 (1.00) | NR3C1PGRCYP3A4ARADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9359294-B2 | Electrophilic reagents for monohalomethylation, their preparation and their uses | HOVIONE INTER LIMITED (CH) | 2016-06-07 | — | — | US | disclosed |
| US-20160130223-A1 | Electrophilic Reagents for Monohalomethylation, Their Preparation and Their Uses | HOVIONE INTER LIMITED (CH) | 2016-05-12 | — | — | US | disclosed |
| US-9290446-B2 | Electrophilic reagents for monohalomethylation, their preparation and their uses | HOVIONE INTER LIMITED (CH) | 2016-03-22 | — | — | US | disclosed |
| US-20130274460-A1 | Electrophilic Reagents for Monohalomethylation, Their Preparation and Their Uses | HOVIONE INTER LIMITED (CH) | 2013-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130274460-A1 | Electrophilic Reagents for Monohalomethylation, Their Preparation and Their Uses | RFC2, FH, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | NR3C1 474/4885PGR 4522/4885CYP3A4 678/4885 |
| US-20160130223-A1 | Electrophilic Reagents for Monohalomethylation, Their Preparation and Their Uses | CBR3, CBR1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | NR3C1 29/4885PGR 640/4885CYP3A4 1747/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.