⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1273779 | 0.79 | FBP1 (0.62) | — | |
| SCHEMBL11834138 | 0.78 | NOS1 (0.52) | — | |
| SCHEMBL1868724 | 0.77 | — | — | |
| Praxadine SCHEMBL94070 | 0.75 | — | — | |
| SCHEMBL881140 | 0.75 | — | — | |
| SCHEMBL1275 | 0.75 | — | — | |
| SCHEMBL1697851 | 0.75 | — | — | |
| Praxadine SCHEMBL52095 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL860891 | 0.73 | — | — | |
| Praxadine SCHEMBL3579034 | 0.73 | NOS1 (0.95) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115925630-B | Preparation method of pyrazole thioamide | 金仓(上海)医药生物科技有限公司 | 2025-03-25 | — | — | CN | claimed |
| EP-4416268-A1 | METHODS FOR PRODUCING CARTILAGE AND BONES | Murdoch Children's Research Institute (AU) | 2024-08-21 | — | — | EP | claimed |
| WO-2023060322-A1 | METHODS FOR PRODUCING CARTILAGE AND BONES | MURDOCH CHILDREN'S RESEARCH INSTITUTE (AU) | 2023-04-20 | — | — | WO | claimed |
| CN-115925630-A | Preparation method of pyrazole thioamide | 金仓(上海)医药生物科技有限公司 | 2023-04-07 | — | — | CN | claimed |
| CN-102086212-B | Antifungal agent-2, 3,4, 5-tetrahydro-4H-benzo [ b ] thiopyrano [4,3-c ] pyrazole-2-carboxamide derivatives | UNIV SHENYANG PHARMACEUTICAL | 2013-06-12 | — | — | CN | claimed |
| CN-102086212-A | Antifungal agent-2, 3,4, 5-tetrahydro-4H-benzo [ b ] thiopyrano [4,3-c ] pyrazole-2-carboxamide derivatives | UNIV SHENYANG PHARMACEUTICAL | 2011-06-08 | — | — | CN | claimed |
| EP-1362852-B1 | PYRAZOLE DERIVATIVE, INTERMEDIATE THEREFOR, PROCESSES FOR PRODUCING THESE, AND HERBICIDE CONTAINING THESE AS ACTIVE INGREDIENT | SAGAMI CHEM RES (JP) | 2011-04-06 | — | — | EP | claimed |
| EP-1807063-A2 | PHARMACEUTICAL COMPOSITIONS COMPRISING CB1 CANNABINOID RECEPTOR ANTAGONISTS AND POTASSIUM CHANNEL OPENERS FOR THE TREATMENT OF DIABETES MELLITUS TYPE I, OBESITY AND RELATED CONDITIONS | Solvay Pharmaceuticals GmbH (DE) | 2007-07-18 | — | — | EP | claimed |
| US-7173055-B1 | Pyrazolecarboxamide and pyrazolethioamide as fungicide | SYNGENTA CROP PROTECTION, INC. (US) | 2007-02-06 | — | — | US | claimed |
| WO-2006045799-A2 | PHARMACEUTICAL COMPOSITIONS COMPRISING CB1 CANNABINOID RECEPTOR ANTAGONISTS AND POTASSIUM CHANNEL OPENERS FOR THE TREATMENT OF DIABETES MELLITUS TYPE I, OBESITY AND RELATED CONDITIONS | SOLVAY PHARMACEUTICALS GMBH (DE) | 2006-05-04 | — | — | WO | claimed |
| US-20050070441-A1 | Pyrazole derivative, intermediate therefor, processes for producing these, and herbicide containing these as active ingredient | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 2005-03-31 | — | — | US | claimed |
| EP-0942904-B1 | 3-THIOCARBAMOYLPYRAZOLE DERIVATIVES AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2004-06-23 | — | — | EP | claimed |
| EP-1362852-A1 | PYRAZOLE DERIVATIVE, INTERMEDIATE THEREFOR, PROCESSES FOR PRODUCING THESE, AND HERBICIDE CONTAINING THESE AS ACTIVE INGREDIENT | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2003-11-19 | — | — | EP | claimed |
| CN-1105709-C | 3-thiocarbamoylpyrazole derivatives as pesticides | BAYER AG (DE) | 2003-04-16 | — | — | CN | claimed |
| US-6265430-B1 | INSECTICIDES, MITICIDES, NEMATOCIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-07-24 | — | — | US | claimed |
| US-20010007876-A1 | 3-THIOCARBAMOYLPYRAZOLE DERIVATIVES AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-07-12 | — | — | US | claimed |
| CN-1239953-A | 3-thiocarbamoylpyrazole derivatives as pesticides | BAYER AG (DE) | 1999-12-29 | — | — | CN | claimed |
| US-20260132380-A1 | Hepatocyte Expansion Methods | KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN (NL) | 2026-05-14 | — | — | US | disclosed |
| EP-0017772-B1 | METHOD OF IMPROVING THE SOLUBILITY OF BIOLOGICALLY ACTIVE AGENTS IN WATER AND IN LOWER ALIPHATIC ALCOHOLS, AND COMPOUNDS HAVING AN IMPROVED SOLUBILITY | BAYER AG (DE) | 1982-07-28 | — | — | EP | disclosed |
| EP-0017772-A1 | Method of improving the solubility of biologically active agents in water and in lower aliphatic alcohols, and compounds having an improved solubility | BAYER AG (DE) | 1980-10-29 | — | — | EP | disclosed |