Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.84 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.84 |
| ▸ | HPGD | P15428 | 3/20 | 0.84 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.84 |
| ▸ | TSHR | P16473 | 1/20 | 0.84 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | CASP1 | P29466 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.52 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.50 |
| ▸ | MAP2 | P11137 | 1/20 | 0.49 |
| ▸ | ALPL | P05186 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | TTK | P33981 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 2/20 | 0.44 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4142958 | 0.92 | KDM4E (1.00) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| Lithium SCHEMBL30669498 | 0.90 | KDM4E (0.96) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL17367227 | 0.89 | KDM4E (0.93) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL8621648 | 0.87 | KDM4E (0.89) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL29130446 | 0.83 | KDM4E (0.82) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL5805631 | 0.82 | KDM4E (0.64) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL28022669 | 0.81 | HSD17B10 (0.78) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL6329236 | 0.79 | KDM4E (0.76) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL4094165 | 0.79 | KDM4E (0.76) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL29130443 | 0.77 | KDM4E (0.71) | KDM4EALDH1A1HPGDHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105358680-B | Methods and compositions for suspension culture of endodermal progenitor cells | 富士费勒姆细胞动力学有限公司 | 2019-06-25 | — | — | CN | disclosed |
| US-20130274233-A1 | MODULATORS OF HEDGEHOG SIGNALING PATHWAY | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2013-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130274233-A1 | MODULATORS OF HEDGEHOG SIGNALING PATHWAY | GLI1, SMO, SHH | KDM4E 3038/4885ALDH1A1 3537/4885HPGD 4128/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.