SCHEMBL17367227

SCHEMBL17367227

O=c1nc(-c2ccc(-c3ccccc3)cc2)c2ccccc2[nH]1

nearest known ligand 0.93

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.93
ALDH1A1 P00352 5/20 0.93
HPGD P15428 4/20 0.93
HSD17B10 Q99714 3/20 0.93
TSHR P16473 1/20 0.93
NPSR1 Q6W5P4 3/20 0.63
MEN1 O00255 2/20 0.63
KMT2A Q03164 2/20 0.63
CASP1 P29466 1/20 0.63
PDE3B Q13370 2/20 0.56
PDE3A Q14432 2/20 0.56
GAA P10253 2/20 0.50
ALPL P05186 1/20 0.50
IDO1 P14902 1/20 0.50
TTK P33981 1/20 0.50
MAPK10 P53779 1/20 0.50
HTR2B P41595 1/20 0.49
HTR5A P47898 1/20 0.49
TDO2 P48775 1/20 0.49
APP P05067 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4142958 0.96 KDM4E (1.00) KDM4EALDH1A1HPGDHSD17B10TSHR
Lithium SCHEMBL30669498 0.95 KDM4E (0.96) KDM4EALDH1A1HPGDHSD17B10TSHR
SCHEMBL8621648 0.95 KDM4E (0.89) KDM4EALDH1A1HPGDHSD17B10TSHR
Urea SCHEMBL15312604 0.89 KDM4E (0.84) KDM4EALDH1A1HPGDHSD17B10TSHR
SCHEMBL29130446 0.87 KDM4E (0.82) KDM4EALDH1A1HPGDHSD17B10TSHR
SCHEMBL6329236 0.87 KDM4E (0.76) KDM4EALDH1A1HPGDHSD17B10TSHR
SCHEMBL4094165 0.87 KDM4E (0.76) KDM4EALDH1A1HPGDHSD17B10TSHR
SCHEMBL17367218 0.87 KDM4E (0.73) KDM4EALDH1A1HPGDHSD17B10TSHR
SCHEMBL28022669 0.85 HSD17B10 (0.78) KDM4EALDH1A1HPGDHSD17B10TSHR
SCHEMBL29130443 0.84 KDM4E (0.71) KDM4EALDH1A1HPGDHSD17B10TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10749118-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-08-18 US disclosed
US-20150380663-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-12-31 US disclosed
US-20150380663-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-12-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150380663-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CYP1A1, CRY1, CYP1B1 KDM4E 3404/4885ALDH1A1 13/4885HPGD 1289/4885
US-10749118-B2 Heterocyclic compound and organic light-emitting device including the same CYP1A1, CRY1, CYP1B1 KDM4E 3404/4885ALDH1A1 13/4885HPGD 1289/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.