SCHEMBL29130446

SCHEMBL29130446

O=c1nc(-c2ccccc2)c2ccccc2[nH]1.c1ccc(N(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.82

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.82
ALDH1A1 P00352 5/20 0.82
HPGD P15428 4/20 0.82
HSD17B10 Q99714 3/20 0.82
TSHR P16473 1/20 0.82
NPSR1 Q6W5P4 3/20 0.57
MEN1 O00255 2/20 0.57
KMT2A Q03164 2/20 0.57
CASP1 P29466 1/20 0.57
PDE3B Q13370 2/20 0.51
PDE3A Q14432 2/20 0.51
POLB P06746 2/20 0.46
GAA P10253 2/20 0.45
ALPL P05186 1/20 0.45
IDO1 P14902 1/20 0.45
TTK P33981 1/20 0.45
MAPK10 P53779 1/20 0.45
APP P05067 2/20 0.43
NPC1 O15118 3/20 0.43
RAB9A P51151 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4142958 0.91 KDM4E (1.00) KDM4EALDH1A1HPGDHSD17B10TSHR
Lithium SCHEMBL30669498 0.89 KDM4E (0.96) KDM4EALDH1A1HPGDHSD17B10TSHR
SCHEMBL17367227 0.87 KDM4E (0.93) KDM4EALDH1A1HPGDHSD17B10TSHR
SCHEMBL8621648 0.85 KDM4E (0.89) KDM4EALDH1A1HPGDHSD17B10TSHR
Urea SCHEMBL15312604 0.83 KDM4E (0.84) KDM4EALDH1A1HPGDHSD17B10TSHR
SCHEMBL27977981 0.80 KDM4E (0.64) KDM4EALDH1A1HPGDHSD17B10TSHR
SCHEMBL28022669 0.80 HSD17B10 (0.78) KDM4EALDH1A1HPGDHSD17B10TSHR
SCHEMBL6329236 0.78 KDM4E (0.76) KDM4EALDH1A1HPGDHSD17B10TSHR
SCHEMBL4094165 0.78 KDM4E (0.76) KDM4EALDH1A1HPGDHSD17B10TSHR
SCHEMBL27977980 0.78 HSD17B10 (0.65) KDM4EALDH1A1HPGDHSD17B10TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117169175-A Method for detecting surface components of lithium metal negative electrode 清华大学 2023-12-05 CN claimed
CN-117169175-A Method for detecting surface components of lithium metal negative electrode 清华大学 2023-12-05 CN disclosed