SCHEMBL28022669

SCHEMBL28022669

O=c1nc(-c2ccncc2)c2ccccc2[nH]1

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.78
KDM4E B2RXH2 2/20 0.78
ALDH1A1 P00352 2/20 0.78
HPGD P15428 2/20 0.78
TSHR P16473 1/20 0.78
MEN1 O00255 1/20 0.57
CASP1 P29466 1/20 0.57
KMT2A Q03164 1/20 0.57
NPSR1 Q6W5P4 1/20 0.57
PDE3B Q13370 2/20 0.51
PDE3A Q14432 2/20 0.51
IMPDH2 P12268 1/20 0.49
MAPK14 Q16539 4/20 0.48
MAPT P10636 1/20 0.46
ALOX15 P16050 1/20 0.46
APOBEC3G Q9HC16 1/20 0.46
CDC7 O00311 1/20 0.45
MAPK13 O15264 1/20 0.45
RAF1 P04049 1/20 0.45
MAPK9 P45984 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8621648 0.90 KDM4E (0.89) HSD17B10KDM4EALDH1A1HPGDTSHR
SCHEMBL4142958 0.88 KDM4E (1.00) HSD17B10KDM4EALDH1A1HPGDTSHR
Lithium SCHEMBL30669498 0.86 KDM4E (0.96) HSD17B10KDM4EALDH1A1HPGDTSHR
SCHEMBL17367227 0.85 KDM4E (0.93) HSD17B10KDM4EALDH1A1HPGDTSHR
SCHEMBL6329236 0.82 KDM4E (0.76) HSD17B10KDM4EALDH1A1HPGDTSHR
SCHEMBL4094165 0.82 KDM4E (0.76) HSD17B10KDM4EALDH1A1HPGDTSHR
Urea SCHEMBL15312604 0.81 KDM4E (0.84) HSD17B10KDM4EALDH1A1HPGDTSHR
SCHEMBL29130446 0.80 KDM4E (0.82) HSD17B10KDM4EALDH1A1HPGDTSHR
SCHEMBL29130443 0.80 KDM4E (0.71) HSD17B10KDM4EALDH1A1HPGDTSHR
SCHEMBL3117686 0.80 KDM4E (0.54) HSD17B10KDM4EALDH1A1HPGDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117169175-A Method for detecting surface components of lithium metal negative electrode 清华大学 2023-12-05 CN claimed
CN-117169175-A Method for detecting surface components of lithium metal negative electrode 清华大学 2023-12-05 CN disclosed
CN-104693211-A Imidazole derivative as antiviral agent and pharmaceutical application thereof NANJING MINGDE NEW DRUG RES AND DEV CO LTD 2015-06-10 CN disclosed