Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EYA3 | Q99504 | 2/20 | 0.60 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.60 |
| ▸ | TTR | P02766 | 1/20 | 0.59 |
| ▸ | THRA | P10827 | 3/20 | 0.57 |
| ▸ | THRB | P10828 | 3/20 | 0.57 |
| ▸ | KDM7A | Q6ZMT4 | 4/20 | 0.57 |
| ▸ | KDM5A | P29375 | 7/20 | 0.56 |
| ▸ | KDM4A | O75164 | 3/20 | 0.56 |
| ▸ | ING2 | Q9H160 | 1/20 | 0.56 |
| ▸ | SIRT3 | Q9NTG7 | 4/20 | 0.55 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | MLNR | O43193 | 1/20 | 0.54 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.54 |
| ▸ | PHF2 | O75151 | 1/20 | 0.54 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15313177 | 0.93 | EYA3 (0.66) | EYA3THRATHRBKDM7AKDM5A | |
| SCHEMBL18743963 | 0.88 | KDM7A (0.65) | EYA3TTRTHRATHRBKDM7A | |
| SCHEMBL18743964 | 0.84 | KDM5A (0.72) | EYA3THRATHRBKDM7AKDM5A | |
| SCHEMBL15313193 | 0.83 | KDM5A (0.76) | THRATHRBKDM7AKDM5AKDM4A | |
| SCHEMBL15313203 | 0.82 | EYA3 (0.67) | EYA3PTPN1TTRTHRATHRB | |
| SCHEMBL18743965 | 0.80 | EYA3 (0.58) | EYA3PTPN1TTRTHRATHRB | |
| SCHEMBL15313334 | 0.80 | SIRT3 (0.84) | THRATHRBKDM7AKDM5AKDM4A | |
| SCHEMBL18744679 | 0.80 | EYA3 (0.39) | EYA3PTPN1TTRTHRATHRB | |
| SCHEMBL25389924 | 0.79 | EYA3 (0.82) | EYA3PTPN1TTRTHRATHRB | |
| SCHEMBL9195719 | 0.79 | EYA3 (0.73) | EYA3PTPN1TTRTHRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9895340-B2 | Fluorinated benzofuran derivatives | SCIFLUOR LIFE SCIENCES, INC. (US) | 2018-02-20 | — | — | US | disclosed |
| US-9895340-B2 | Fluorinated benzofuran derivatives | SCIFLUOR LIFE SCIENCES, INC. (US) | 2018-02-20 | — | — | US | disclosed |
| US-20170189370-A1 | FLUORINATED BENZOFURAN DERIVATIVES | FELIQS CORPORATION (JP) | 2017-07-06 | — | — | US | disclosed |
| US-20170189370-A1 | FLUORINATED BENZOFURAN DERIVATIVES | FELIQS CORPORATION (JP) | 2017-07-06 | — | — | US | disclosed |
| US-20170189370-A1 | FLUORINATED BENZOFURAN DERIVATIVES | FELIQS CORPORATION (JP) | 2017-07-06 | — | — | US | disclosed |
| EP-2838890-B1 | FLUORINATED BENZOFURAN DERIVATIVES | SCIFLUOR LIFE SCIENCES INC (US) | 2017-06-21 | — | — | EP | disclosed |
| EP-2838890-B1 | FLUORINATED BENZOFURAN DERIVATIVES | SCIFLUOR LIFE SCIENCES INC (US) | 2017-06-21 | — | — | EP | disclosed |
| US-9624189-B2 | Fluorinated benzofuran derivatives | SCIFLUOR LIFE SCIENCES, INC. (US) | 2017-04-18 | — | — | US | disclosed |
| US-9624189-B2 | Fluorinated benzofuran derivatives | SCIFLUOR LIFE SCIENCES, INC. (US) | 2017-04-18 | — | — | US | disclosed |
| US-9624189-B2 | Fluorinated benzofuran derivatives | SCIFLUOR LIFE SCIENCES, INC. (US) | 2017-04-18 | — | — | US | disclosed |
| EP-2838890-A1 | FLUORINATED BENZOFURAN DERIVATIVES | Scifluor Life Sciences, LLC (US) | 2015-02-25 | — | — | EP | disclosed |
| WO-2013158251-A1 | FLUORINATED BENZOFURAN DERIVATIVES | SCIFLUOR LIFE SCIENCES, LLC (US) | 2013-10-24 | — | — | WO | disclosed |
| US-20130274325-A1 | Fluorinated Benzofuran Derivatives | FELIQS CORPORATION (JP) | 2013-10-17 | — | — | US | disclosed |
| US-20130274325-A1 | Fluorinated Benzofuran Derivatives | FELIQS CORPORATION (JP) | 2013-10-17 | — | — | US | disclosed |
| US-20130274325-A1 | Fluorinated Benzofuran Derivatives | FELIQS CORPORATION (JP) | 2013-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130274325-A1 | Fluorinated Benzofuran Derivatives | FABP3, TNNI3, TNNT2 | EYA3 3283/4885PTPN1 4361/4885TTR 1341/4885 |
| US-20170189370-A1 | FLUORINATED BENZOFURAN DERIVATIVES | FABP3, TNNI3, TNNT2 | EYA3 3283/4885PTPN1 4361/4885TTR 1341/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.