Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EYA3 | Q99504 | 5/20 | 0.39 |
| ▸ | KDM5A | P29375 | 6/20 | 0.39 |
| ▸ | KDM4A | O75164 | 3/20 | 0.39 |
| ▸ | ING2 | Q9H160 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 3/20 | 0.38 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | DRD1 | P21728 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | KDM7A | Q6ZMT4 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18744671 | 0.94 | KDM5A (0.46) | EYA3KDM5AKDM4AING2THRA | |
| SCHEMBL18744670 | 0.84 | KDM5A (0.53) | EYA3KDM5AKDM4AING2THRA | |
| SCHEMBL18744672 | 0.83 | EYA3 (0.43) | EYA3CYP2C19SLC22A12PTPN1THRB | |
| SCHEMBL18744699 | 0.81 | KDM5A (0.60) | KDM5AKDM4AING2THRATHRB | |
| SCHEMBL15313191 | 0.80 | EYA3 (0.60) | EYA3KDM5AKDM4AING2PTPN1 | |
| SCHEMBL18744673 | 0.77 | SIRT3 (0.46) | KDM5ACYP2C19THRATHRBSIRT3 | |
| SCHEMBL18744668 | 0.77 | EYA3 (0.62) | EYA3KDM5AKDM4AING2CYP2C19 | |
| SCHEMBL15313177 | 0.74 | EYA3 (0.66) | EYA3KDM5AKDM4AING2THRA | |
| SCHEMBL25815021 | 0.68 | EYA3 (0.60) | EYA3CYP2C19SLC22A12PTPN1THRB | |
| SCHEMBL18743963 | 0.68 | KDM7A (0.65) | EYA3KDM5AKDM4AING2THRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9895340-B2 | Fluorinated benzofuran derivatives | SCIFLUOR LIFE SCIENCES, INC. (US) | 2018-02-20 | — | — | US | disclosed |
| US-20170189370-A1 | FLUORINATED BENZOFURAN DERIVATIVES | FELIQS CORPORATION (JP) | 2017-07-06 | — | — | US | disclosed |
| EP-2838890-B1 | FLUORINATED BENZOFURAN DERIVATIVES | SCIFLUOR LIFE SCIENCES INC (US) | 2017-06-21 | — | — | EP | disclosed |
| US-9624189-B2 | Fluorinated benzofuran derivatives | SCIFLUOR LIFE SCIENCES, INC. (US) | 2017-04-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170189370-A1 | FLUORINATED BENZOFURAN DERIVATIVES | FABP3, TNNI3, TNNT2 | EYA3 3283/4885KDM5A 2353/4885KDM4A 3178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.