Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 6/20 | 0.48 |
| ▸ | NAALAD2 | Q9Y3Q0 | 3/20 | 0.48 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.48 |
| ▸ | GGH | Q92820 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 2/20 | 0.38 |
| ▸ | FNTB | P49356 | 2/20 | 0.38 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.36 |
| ▸ | KDM4A | O75164 | 2/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.36 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.36 |
| ▸ | TET3 | O43151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10355087 | 0.84 | FOLH1 (0.50) | FOLH1NAALAD2RIMKLAGGHGAA | |
| SCHEMBL9840749 | 0.81 | CA2 (0.37) | GAAFNTAFNTB | |
| SCHEMBL3093833 | 0.78 | GGH (0.50) | FOLH1NAALAD2RIMKLAGGH | |
| SCHEMBL910825 | 0.78 | FOLH1 (0.52) | FOLH1NAALAD2RIMKLAGGHGAA | |
| SCHEMBL28972790 | 0.78 | FOLH1 (0.52) | FOLH1NAALAD2RIMKLAGGHGAA | |
| SCHEMBL910826 | 0.78 | FOLH1 (0.52) | FOLH1NAALAD2RIMKLAGGHGAA | |
| SCHEMBL910807 | 0.78 | FOLH1 (0.52) | FOLH1NAALAD2RIMKLAGGHGAA | |
| Hydrochloric Acid SCHEMBL8726784 | 0.76 | FOLH1 (0.50) | FOLH1NAALAD2RIMKLAGGHGAA | |
| SCHEMBL27683390 | 0.76 | FOLH1 (0.50) | FOLH1NAALAD2RIMKLAGGHGAA | |
| Hydrochloric Acid SCHEMBL8726781 | 0.76 | FOLH1 (0.50) | FOLH1NAALAD2RIMKLAGGHGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10030103-B2 | Stable helical ionic polypeptides | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2018-07-24 | — | — | US | disclosed |
| EP-2646048-B1 | STABLE HELICAL IONIC POLYPEPTIDES | UNIV ILLINOIS (US) | 2017-11-01 | — | — | EP | disclosed |
| US-20160215093-A1 | STABLE HELICAL IONIC POLYPEPTIDES | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2016-07-28 | — | — | US | disclosed |
| US-9243040-B2 | Stable helical ionic polypeptides | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2016-01-26 | — | — | US | disclosed |
| US-20130274173-A1 | STABLE HELICAL IONIC POLYPEPTIDES | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2013-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10030103-B2 | Stable helical ionic polypeptides | GHITM, SLC7A1, PICALM | FOLH1 777/4885NAALAD2 3601/4885RIMKLA 3534/4885 |
| US-20130274173-A1 | STABLE HELICAL IONIC POLYPEPTIDES | GHITM, SLC7A1, PICALM | FOLH1 777/4885NAALAD2 3601/4885RIMKLA 3534/4885 |
| US-20160215093-A1 | STABLE HELICAL IONIC POLYPEPTIDES | GHITM, SLC7A1, PICALM | FOLH1 777/4885NAALAD2 3601/4885RIMKLA 3534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.