Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 9/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 9/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 9/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 9/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 9/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29422910 | 0.84 | CYP2D6 (0.38) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL20086778 | 0.74 | CHRNB2 (0.57) | — | |
| SCHEMBL20086777 | 0.74 | CHRNB2 (0.57) | — | |
| SCHEMBL20086796 | 0.74 | CHRNB2 (0.57) | — | |
| SCHEMBL20086775 | 0.74 | CHRNB2 (0.57) | — | |
| SCHEMBL9370820 | 0.72 | CHRM2 (0.47) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL16887928 | 0.69 | ALOX15 (0.74) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL14245531 | 0.69 | ALOX15 (0.74) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL29883811 | 0.69 | ALOX15 (0.74) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL11387720 | 0.65 | CHRNB2 (0.62) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8557804-B2 | Nicotinic receptor agonists for the treatment of inflammatory diseases | UNIVERSITE LAVAL (CA) | 2013-10-15 | — | — | US | disclosed |