Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12575414 | 0.86 | ALDH1A1 (0.46) | DGKAADRA2AADRA1AHSD17B10TSHR | |
| SCHEMBL15313639 | 0.86 | ALDH1A1 (0.46) | DGKAADRA2AADRA1AHSD17B10TSHR | |
| SCHEMBL12575518 | 0.86 | EPHX2 (0.39) | DGKAADRA2AADRA1AHSD17B10TSHR | |
| SCHEMBL12575410 | 0.85 | ADRA2A (0.36) | DGKAADRA2AADRA1AHSD17B10TSHR | |
| SCHEMBL14616913 | 0.83 | DGKA (0.41) | DGKAADRA2AADRA1AHSD17B10TSHR | |
| SCHEMBL22662461 | 0.83 | DGKA (0.43) | DGKAADRA2AADRA1AHSD17B10TSHR | |
| SCHEMBL17639964 | 0.81 | DGKA (0.42) | DGKAADRA2AADRA1AHSD17B10TSHR | |
| SCHEMBL22510580 | 0.81 | ADRA2A (0.48) | DGKAADRA2AADRA1AHSD17B10TSHR | |
| SCHEMBL2302053 | 0.81 | ADRA2A (0.48) | DGKAADRA2AADRA1AHSD17B10TSHR | |
| SCHEMBL13268865 | 0.81 | ADRA2A (0.48) | DGKAADRA2AADRA1AHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8558019-B2 | Thiolated paclitaxels for reaction with gold nanoparticles as drug delivery agents | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2013-10-15 | — | — | US | disclosed |