Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 1/20 | 0.54 |
| ▸ | NAAA | Q02083 | 4/20 | 0.54 |
| ▸ | MMP1 | P03956 | 1/20 | 0.51 |
| ▸ | MMP3 | P08254 | 1/20 | 0.51 |
| ▸ | MMP7 | P09237 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | MMP8 | P22894 | 1/20 | 0.51 |
| ▸ | MMP12 | P39900 | 1/20 | 0.51 |
| ▸ | MMP13 | P45452 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | MLYCD | O95822 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13531427 | 1.00 | IDH1 (0.54) | IDH1NAAAMMP1MMP3MMP7 | |
| SCHEMBL13469357 | 0.93 | IDH1 (0.62) | IDH1NAAAMMP1MMP3MMP7 | |
| SCHEMBL13469336 | 0.91 | IDH1 (0.64) | IDH1NAAAMMP1MMP3MMP7 | |
| SCHEMBL19978233 | 0.88 | IDH1 (0.60) | IDH1MMP1MMP3MMP7MMP9 | |
| SCHEMBL13469343 | 0.88 | IDH1 (0.64) | IDH1MMP1MMP3MMP7MMP9 | |
| SCHEMBL18427362 | 0.82 | IDH1 (0.64) | IDH1MMP1MMP3MMP7MMP9 | |
| SCHEMBL15314089 | 0.81 | IDH1 (0.55) | IDH1MMP1MMP3MMP7MMP9 | |
| SCHEMBL16622505 | 0.81 | IDH1 (0.51) | IDH1MMP1MMP3MMP7MMP9 | |
| SCHEMBL11990370 | 0.78 | IDH1 (0.55) | IDH1MMP1MMP3MMP7MMP9 | |
| SCHEMBL13469136 | 0.78 | IDH1 (0.58) | IDH1MMP1MMP3MMP7MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9556122-B2 | Luminescent 1-hydroxy-2-pyridinone chelates of lanthanides | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-01-31 | — | — | US | disclosed |
| US-20140039169-A1 | LUMINESCENT 1-HYDROXY-2-PYRIDINONE CHELATES OF LANTHANIDES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2014-02-06 | — | — | US | disclosed |
| US-8557601-B2 | Luminescent 1-hydroxy-2-pyridinone chelates of lanthanides | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140039169-A1 | LUMINESCENT 1-HYDROXY-2-PYRIDINONE CHELATES OF LANTHANIDES | PLPBP, HPD, LASP1 | IDH1 25/4885NAAA 2044/4885MMP1 945/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.