SCHEMBL15314784

SCHEMBL15314784

CCOC(=O)C(F)(F)c1ccccc1C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
PIN1 Q13526 1/20 0.46
TSHR P16473 2/20 0.43
MAPT P10636 1/20 0.43
ALDH1A1 P00352 2/20 0.41
RECQL P46063 1/20 0.41
MMP8 P22894 1/20 0.41
HDAC3 O15379 1/20 0.41
HDAC4 P56524 1/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
KMT2A Q03164 2/20 0.40
TAAR1 Q96RJ0 2/20 0.40
LMNA P02545 1/20 0.40
MEN1 O00255 1/20 0.40
HTT P42858 1/20 0.40
THRB P10828 1/20 0.40
KDM4E B2RXH2 2/20 0.40
NLRP3 Q96P20 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13199349 0.91 PIN1 (0.50) POLBNPSR1PIN1TSHRMAPT
SCHEMBL31306500 0.85 CA12 (0.47) POLBNPSR1PIN1TSHRMAPT
SCHEMBL1477878 0.85 POLB (0.46) POLBNPSR1PIN1TSHRMAPT
SCHEMBL31306448 0.83 ALDH1A1 (0.45) POLBNPSR1PIN1TSHRMAPT
SCHEMBL30682977 0.83 PIN1 (0.47) POLBNPSR1PIN1TSHRMAPT
SCHEMBL9282135 0.83 ALDH1A1 (0.45) POLBNPSR1PIN1TSHRMAPT
SCHEMBL19925655 0.83 PIN1 (0.47) POLBNPSR1PIN1TSHRMAPT
SCHEMBL22426150 0.82 TSHR (0.47) POLBNPSR1PIN1TSHRMAPT
SCHEMBL30039482 0.82 MAPT (0.50) POLBNPSR1PIN1MAPTALDH1A1
SCHEMBL17681857 0.82 TSHR (0.47) POLBNPSR1PIN1TSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2650276-B1 METHOD FOR PRODUCING BETA-FLUOROALCOHOL CENTRAL GLASS CO LTD (JP) 2017-01-25 EP disclosed
US-8658840-B2 Method for producing β-fluoroalcohol CENTRAL GLASS COMPANY, LIMITED (JP) 2014-02-25 US disclosed
US-8658840-B2 Method for producing β-fluoroalcohol CENTRAL GLASS COMPANY, LIMITED (JP) 2014-02-25 US disclosed
US-20130303774-A1 Method For Producing Beta-Fluoroalcohol CENTRAL GLASS COMPANY, LIMITED (JP) 2013-11-14 US disclosed
US-20130303774-A1 Method For Producing Beta-Fluoroalcohol CENTRAL GLASS COMPANY, LIMITED (JP) 2013-11-14 US disclosed
EP-2650276-A1 METHOD FOR PRODUCING -FLUOROALCOHOL Central Glass Company, Limited (JP) 2013-10-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130303774-A1 Method For Producing Beta-Fluoroalcohol FNTB, ADH1A, EBP POLB 215/4885NPSR1 4346/4885PIN1 3718/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.