SCHEMBL1531658

SCHEMBL1531658

CC1=Cc2c(-c3ccccc3)cccc2C1[Zr](C1C(C)=Cc2c(-c3ccccc3)cccc21)[SiH](C)C.C[Si](C)(Cl)Cl

nearest known ligand 0.30

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 1/20 0.30
HTR7 P34969 1/20 0.30
HTR2B P41595 1/20 0.30
TMEM97 Q5BJF2 1/20 0.30
SIGMAR1 Q99720 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL215863 0.93 BRD4 (0.32) HTR1AHTR7HTR2BTMEM97SIGMAR1
SCHEMBL29442977 0.93 BRD4 (0.32) HTR1AHTR7HTR2BTMEM97SIGMAR1
Hydrochloric Acid SCHEMBL819254 0.92 BRD4 (0.31)
SCHEMBL5363333 0.91 BRD4 (0.31)
SCHEMBL5360910 0.88 BRD4 (0.31)
SCHEMBL9069407 0.87
SCHEMBL61921 0.84 MAOB (0.33)
SCHEMBL2234309 0.84 EDNRB (0.30)
Hydrochloric Acid SCHEMBL2234623 0.83
SCHEMBL5351378 0.82 ENPP3 (0.33) SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7915367-B2 Process for the manufacture of branched polypropylene BOREALIS TECHNOLOGY OY (FI) 2011-03-29 US disclosed
US-20090264606-A1 PROCESS FOR THE MANUFACTURE OF BRANCHED POLYPROPYLENE BOREALIS AG (AT) 2009-10-22 US disclosed
EP-2097461-A1 PROCESS FOR THE MANUFACTURE OF BRANCHED POLYPROPYLENE Borealis Technology OY (FI) 2009-09-09 EP disclosed
WO-2008080886-A1 PROCESS FOR THE MANUFACTURE OF BRANCHED POLYPROPYLENE BOREALIS TECHNOLOGY OY (FI) 2008-07-10 WO disclosed