SCHEMBL5363333

SCHEMBL5363333

CC1=Cc2c(-c3ccc(-c4ccccc4)cc3)cccc2C1[Zr](C1C(C)=Cc2c(-c3ccc(-c4ccccc4)cc3)cccc21)[SiH](C)C

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.31
PDCD1 Q15116 1/20 0.30
CD274 Q9NZQ7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL215863 0.97 BRD4 (0.32) BRD4PDCD1CD274
SCHEMBL29442977 0.97 BRD4 (0.32) BRD4PDCD1CD274
Hydrochloric Acid SCHEMBL819254 0.96 BRD4 (0.31) BRD4PDCD1CD274
SCHEMBL5360910 0.92 BRD4 (0.31) BRD4PDCD1CD274
SCHEMBL1531658 0.91 HTR1A (0.30)
SCHEMBL9069407 0.91
SCHEMBL2234309 0.90 EDNRB (0.30)
Hydrochloric Acid SCHEMBL2234623 0.89
SCHEMBL61921 0.87 MAOB (0.33)
SCHEMBL2234772 0.85 BRD4 (0.32) BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7297747-B2 Polymerization process and polymer composition EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-11-20 US disclosed
US-20050059785-A1 Polymerization process and polymer composition HART JAMES R (US) 2005-03-17 US disclosed
US-20050054520-A1 Metallocenes and catalyst compositions derived therefrom EXXONMOBIL CHEMICAL PATENT INC. 2005-03-10 US disclosed