Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.53 |
| ▸ | CTSB | P07858 | 1/20 | 0.53 |
| ▸ | CTSK | P43235 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.48 |
| ▸ | HTR3B | O95264 | 2/20 | 0.48 |
| ▸ | HTR3A | P46098 | 2/20 | 0.48 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.48 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11206076 | 0.86 | CTSL (0.54) | CTSLCTSBCTSKHPGDALOX15 | |
| SCHEMBL11206072 | 0.86 | CTSL (0.54) | CTSLCTSBCTSKHPGDALOX15 | |
| SCHEMBL29564585 | 0.84 | HPGD (0.53) | HPGDALOX15MAPTLMNAGAA | |
| Hydrochloric Acid SCHEMBL29564409 | 0.83 | HPGD (0.51) | HPGDALOX15MAPTLMNAGAA | |
| SCHEMBL31425213 | 0.81 | CA12 (0.50) | HPGDGAASMN1; SMN2MEN1KMT2A | |
| SCHEMBL28169678 | 0.80 | TDP1 (0.48) | CTSLCTSBCTSKHPGDALOX15 | |
| SCHEMBL5674194 | 0.80 | TDP1 (0.48) | CTSLCTSBCTSKHPGDALOX15 | |
| SCHEMBL1532302 | 0.77 | LMNA (0.48) | HPGDALOX15MAPTLMNAGAA | |
| SCHEMBL14691489 | 0.76 | HPGD (0.55) | HPGDALOX15MAPTLMNAGAA | |
| SCHEMBL8745474 | 0.76 | HPGD (0.55) | HPGDALOX15MAPTLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011029043-A1 | HETEROARYL BTK INHIBITORS | BIOGEN IDEC MA INC. (US) | 2011-03-10 | — | — | WO | disclosed |