Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | BTK | Q06187 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.36 |
| ▸ | ACP1 | P24666 | 1/20 | 0.36 |
| ▸ | GRN | P28799 | 1/20 | 0.36 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.36 |
| ▸ | PIP4K2A | P48426 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1531545 | 0.84 | GRN (0.46) | L3MBTL1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL1531548 | 0.84 | GRN (0.46) | L3MBTL1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL1532302 | 0.84 | LMNA (0.48) | MAPTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL8996235 | 0.77 | HTT (0.38) | L3MBTL1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL8996290 | 0.77 | HTT (0.38) | L3MBTL1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL11497907 | 0.76 | ALDH1A1 (0.44) | MAPTMEN1KMT2ABTKALDH1A1 | |
| SCHEMBL1531518 | 0.75 | MEN1 (0.44) | L3MBTL1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL1531587 | 0.74 | GRM4 (0.41) | MAPTMEN1KMT2AGAAGRM4 | |
| SCHEMBL1531584 | 0.74 | GRM4 (0.41) | MAPTMEN1KMT2AGAAGRM4 | |
| SCHEMBL28009264 | 0.72 | GAA (0.50) | L3MBTL1MAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011029043-A1 | HETEROARYL BTK INHIBITORS | BIOGEN IDEC MA INC. (US) | 2011-03-10 | — | — | WO | disclosed |