SCHEMBL15317154

SCHEMBL15317154

COc1cc(C)cc(C(=O)c2ccc(O)cc2)c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.50
MAPT P10636 3/20 0.50
HPGD P15428 3/20 0.50
HTT P42858 2/20 0.50
ESR1 P03372 1/20 0.50
ESR2 Q92731 1/20 0.50
PKM P14618 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
TUBB4A P04350 1/20 0.49
TUBB P07437 1/20 0.49
TUBA3C P0DPH7 1/20 0.49
TUBA1B P68363 1/20 0.49
TUBA4A P68366 1/20 0.49
TUBB4B P68371 1/20 0.49
TUBB3 Q13509 1/20 0.49
TUBB2A Q13885 1/20 0.49
TUBB8 Q3ZCM7 1/20 0.49
TUBA3E Q6PEY2 1/20 0.49
TUBA1A Q71U36 1/20 0.49
TUBA1C Q9BQE3 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15431499 0.90 TUBB4A (0.60) LMNAMAPTHPGDHTTSMN1; SMN2
SCHEMBL11914196 0.86 ALDH1A1 (0.46) MAPTSMN1; SMN2TUBB4ATUBBTUBA3C
SCHEMBL15172000 0.85 MEN1 (0.52) LMNAHPGDHTTSMN1; SMN2TUBB4A
SCHEMBL15443977 0.84 TUBB4A (0.50) LMNAMAPTHPGDHTTTUBB4A
SCHEMBL10958957 0.84 LMNA (0.65) LMNAMAPTHPGDHTTESR1
SCHEMBL15317152 0.83 TUBB4A (0.57) LMNAMAPTHPGDHTTSMN1; SMN2
SCHEMBL15317153 0.83 TUBB4A (0.57) LMNAMAPTHPGDHTTESR1
SCHEMBL15686208 0.82 TUBB4A (0.64) LMNAMAPTHPGDHTTTUBB4A
SCHEMBL9999619 0.82 LMNA (0.61) LMNAMAPTHPGDHTTSMN1; SMN2
SCHEMBL10421782 0.82 CA1 (0.59) LMNAMAPTHPGDHTTESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130273450-A1 TRI-BLOCK COPOLYMER AND ELECTROLYTE MEMBRANE MADE FROM THE SAME LG CHEM, LTD. (KR) 2013-10-17 US disclosed
US-20130273450-A1 TRI-BLOCK COPOLYMER AND ELECTROLYTE MEMBRANE MADE FROM THE SAME LG CHEM, LTD. (KR) 2013-10-17 US disclosed