SCHEMBL15317537

SCHEMBL15317537

CCCc1cc(F)c(C(F)(F)Oc2ccc(C(F)(F)Oc3cc(F)c(F)c(F)c3)c(F)c2)c(F)c1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15317517 0.91 FFAR1 (0.33) MAOB
SCHEMBL14226610 0.91 THRB (0.31)
SCHEMBL7722746 0.89 MAOB (0.31) MAOB
SCHEMBL14226642 0.89 GRM2 (0.33)
SCHEMBL7731510 0.88 DAO (0.34) MAOB
SCHEMBL14226537 0.87 KIF11 (0.39) MAOB
SCHEMBL7729113 0.86 MAOB (0.32) MAOB
SCHEMBL14226769 0.86 S1PR1 (0.39)
SCHEMBL14226855 0.85 S1PR1 (0.32)
SCHEMBL15317519 0.85 S1PR1 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9133397-B2 Tricyclic compound having a plurality of CF2O bonding groups, liquid crystal composition, and liquid crystal display device JNC CORPORATION (JP) 2015-09-15 US disclosed
US-9133397-B2 Tricyclic compound having a plurality of CF2O bonding groups, liquid crystal composition, and liquid crystal display device JNC CORPORATION (JP) 2015-09-15 US disclosed
US-20130271719-A1 TRICYCLIC COMPOUND HAVING A PLURALITY OF CF2O BONDING GROUPS, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-10-17 US disclosed
US-20130271719-A1 TRICYCLIC COMPOUND HAVING A PLURALITY OF CF2O BONDING GROUPS, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-10-17 US disclosed