Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.73 |
| ▸ | MEN1 | O00255 | 2/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.73 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | HTT | P42858 | 3/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.65 |
| ▸ | NPC1 | O15118 | 1/20 | 0.65 |
| ▸ | PKM | P14618 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 3/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | RECQL | P46063 | 2/20 | 0.60 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.60 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7161373 | 0.82 | ALDH1A1 (0.66) | ALDH1A1MEN1KMT2AALOX15SMN1; SMN2 | |
| SCHEMBL4418772 | 0.81 | NPSR1 (0.63) | ALDH1A1KMT2ASMN1; SMN2TSHRHTT | |
| SCHEMBL5123738 | 0.80 | ALDH1A1 (0.77) | ALDH1A1MEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL1474478 | 0.80 | NPC1 (1.00) | ALDH1A1MEN1KMT2AALOX15HSD17B10 | |
| SCHEMBL7082686 | 0.80 | TSHR (0.73) | ALDH1A1MEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL16266238 | 0.79 | ALDH1A1 (1.00) | ALDH1A1MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL9130703 | 0.79 | FES (0.81) | ALDH1A1MEN1KMT2ASMN1; SMN2PKM | |
| SCHEMBL29460250 | 0.79 | FES (0.81) | ALDH1A1MEN1KMT2ASMN1; SMN2PKM | |
| SCHEMBL1161997 | 0.78 | NAMPT (0.75) | ALDH1A1KMT2AHTTLMNAUSP2 | |
| SCHEMBL1568226 | 0.78 | ALDH1A1 (0.72) | ALDH1A1MEN1KMT2ATSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013149336-A1 | 5-NITROFURAN-2-CARBOXAMIDE DERIVATIVES FOR INHIBITING CENTROSOMAL CLUSTERING | BRITISH COLUMBIA CANCER AGENCY BRANCH (CA) | 2013-10-10 | — | — | WO | claimed |
| WO-2013149336-A1 | 5-NITROFURAN-2-CARBOXAMIDE DERIVATIVES FOR INHIBITING CENTROSOMAL CLUSTERING | BRITISH COLUMBIA CANCER AGENCY BRANCH (CA) | 2013-10-10 | — | — | WO | disclosed |