Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | CTSG | P08311 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 3/20 | 0.32 |
| ▸ | ERN1 | O75460 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14458907 | 0.95 | ALDH1A1 (0.38) | RAB9ASIGMAR1ALDH1A1GAACHRM1 | |
| SCHEMBL8864772 | 0.83 | RAB9A (0.37) | RAB9ASIGMAR1ALDH1A1GAACHRM1 | |
| SCHEMBL15275741 | 0.83 | RAB9A (0.40) | RAB9ASIGMAR1ALDH1A1GAACHRM1 | |
| SCHEMBL8864765 | 0.83 | RAB9A (0.37) | RAB9ASIGMAR1ALDH1A1GAACHRM1 | |
| SCHEMBL8865091 | 0.82 | POLB (0.54) | RAB9ASIGMAR1ALDH1A1GAACHRM1 | |
| SCHEMBL8865107 | 0.82 | POLB (0.54) | RAB9ASIGMAR1ALDH1A1GAACHRM1 | |
| SCHEMBL8667874 | 0.82 | RAB9A (0.60) | RAB9AALDH1A1LMNA | |
| SCHEMBL8667871 | 0.82 | RAB9A (0.60) | RAB9AALDH1A1LMNA | |
| SCHEMBL10683300 | 0.82 | RAB9A (0.60) | RAB9AALDH1A1LMNA | |
| SCHEMBL28549824 | 0.81 | RAB9A (0.38) | RAB9ASIGMAR1ALDH1A1GAACHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112778330-A | Pyridone-containing polycyclic derivative inhibitor, and preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2021-05-11 | — | — | CN | disclosed |
| WO-2013149996-A9 | SUBSTITUTED TRICYCLIC COMPOUNDS WITH ACTIVITY TOWARDS EP1 RECEPTORS | ALMIRALL, S.A. (ES) | 2014-02-20 | — | — | WO | disclosed |
| WO-2013149996-A1 | SUBSTITUTED TRICYCLIC COMPOUNDS WITH ACTIVITY TOWARDS EP1 RECEPTORS | ALMIRALL, S.A. (ES) | 2013-10-10 | — | — | WO | disclosed |