SCHEMBL8864765

SCHEMBL8864765

C=CCOC(=O)N1CCC[C@H]1C=O

nearest known ligand 0.40

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 2/20 0.37
SIGMAR1 Q99720 1/20 0.37
ALDH1A1 P00352 1/20 0.35
GAA P10253 1/20 0.35
CHRM1 P11229 1/20 0.34
ELANE P08246 1/20 0.33
CTSG P08311 1/20 0.33
CYP19A1 P11511 1/20 0.33
POLB P06746 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
HCRTR2 O43614 1/20 0.32
LMNA P02545 1/20 0.32
MAPK1 P28482 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8864772 1.00 RAB9A (0.37) RAB9ASIGMAR1ALDH1A1GAACHRM1
SCHEMBL15322317 0.83 RAB9A (0.39) RAB9ASIGMAR1ALDH1A1GAACHRM1
SCHEMBL9192808 0.83 SIGMAR1 (0.35) RAB9ASIGMAR1ALDH1A1GAACHRM1
SCHEMBL9194135 0.83 SIGMAR1 (0.35) RAB9ASIGMAR1ALDH1A1GAACHRM1
SCHEMBL9194136 0.83 SIGMAR1 (0.35) RAB9ASIGMAR1ALDH1A1GAACHRM1
SCHEMBL9192814 0.83 SIGMAR1 (0.35) RAB9ASIGMAR1ALDH1A1GAACHRM1
SCHEMBL13532420 0.81 RAB9A (0.43) RAB9AALDH1A1GAAELANECTSG
SCHEMBL12133179 0.81 RAB9A (0.43) RAB9AALDH1A1GAAELANECTSG
SCHEMBL15275741 0.81 RAB9A (0.40) RAB9ASIGMAR1ALDH1A1GAACHRM1
SCHEMBL9697758 0.80 FFAR1 (0.39) RAB9ASIGMAR1ALDH1A1GAACHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5672701-A 4-substituted alkyl carbapenem antibiotics BRISTOL-MYERS SQUIBB COMPANY (US) 1997-09-30 US disclosed
CN-1030918-C 4-substituted alkyl carbapenem antibiotics BRISTOL MYERS SQUIBB CO (US) 1996-02-07 CN disclosed
US-5081237-A Chemical intermediates for bactericides FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) 1992-01-14 US disclosed
US-4923857-A CARBAPENICILLINS FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) 1990-05-08 US disclosed
EP-0330108-A1 3-Alkenyl-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid compounds FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1989-08-30 EP disclosed