Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PRKCA | P17252 | 3/20 | 0.36 |
| ▸ | TLR2 | O60603 | 3/20 | 0.33 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.32 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.32 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.32 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.31 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl Alcohol SCHEMBL15324148 | 0.88 | PRKCA (0.44) | SLC7A5PRKCAPRKCEPRKCQPRKCD | |
| Propylene Glycol SCHEMBL15323380 | 0.85 | PRKCA (0.42) | SLC7A5PRKCAPRKCEPRKCQPRKCD | |
| SCHEMBL15323800 | 0.85 | SLC7A5 (0.33) | SLC7A5ALDH1A1LMNATLR2 | |
| SCHEMBL15323883 | 0.84 | SLC7A5 (0.34) | SLC7A5ALDH1A1LMNAPRKCA | |
| SCHEMBL15323181 | 0.83 | MARS1 (0.33) | SLC7A5TLR2 | |
| SCHEMBL720968 | 0.81 | ALDH1A1 (0.46) | ALDH1A1LMNAPRKCAPRKCEPRKCQ | |
| Propylene Glycol SCHEMBL15324013 | 0.80 | PRKCA (0.42) | PRKCAPRKCEPRKCQPRKCD | |
| Leucine SCHEMBL15322741 | 0.79 | SLC7A5 (0.53) | SLC7A5SLC1A3SLC1A2 | |
| Succinic Acid SCHEMBL15323069 | 0.77 | PRKCA (0.40) | SLC7A5PRKCAPRKCEPRKCQPRKCD | |
| SCHEMBL4762688 | 0.75 | SLC7A5 (0.54) | SLC7A5ALDH1A1SLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2836832-A1 | EARLY TRIMESTER SCREENING FOR EARLY- AND LATE-ONSET PREECLAMPSIA | Wayne State University (US) | 2015-02-18 | — | — | EP | disclosed |
| WO-2013155458-A1 | EARLY TRIMESTER SCREENING FOR EARLY- AND LATE-ONSET PREECLAMPSIA | WAYNE STATE UNIVERSITY (US) | 2013-10-17 | — | — | WO | disclosed |