Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.49 |
| ▸ | BHMT | Q93088 | 7/20 | 0.42 |
| ▸ | BHMT2 | Q9H2M3 | 1/20 | 0.42 |
| ▸ | NOS3 | P29474 | 4/20 | 0.39 |
| ▸ | NOS1 | P29475 | 4/20 | 0.39 |
| ▸ | NOS2 | P35228 | 4/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Racemethionine SCHEMBL15322970 | 1.00 | GSR (0.49) | GSRBHMTBHMT2NOS3NOS1 | |
| Lysine SCHEMBL8679690 | 0.94 | GSR (0.57) | GSRBHMTBHMT2NOS3NOS1 | |
| Lysine SCHEMBL8679695 | 0.94 | GSR (0.57) | GSRBHMTBHMT2NOS3NOS1 | |
| Methionine SCHEMBL15323594 | 0.93 | GSR (0.45) | GSRBHMTBHMT2NOS3NOS1 | |
| Racemethionine SCHEMBL15323591 | 0.93 | GSR (0.45) | GSRBHMTBHMT2NOS3NOS1 | |
| Lysine SCHEMBL16876653 | 0.91 | GSR (0.53) | GSRBHMTBHMT2NOS3NOS1 | |
| Lysine SCHEMBL16876651 | 0.91 | GSR (0.53) | GSRBHMTBHMT2NOS3NOS1 | |
| Ornithine SCHEMBL15322972 | 0.90 | GSR (0.42) | GSRBHMTBHMT2NOS3NOS1 | |
| Racemethionine SCHEMBL23924294 | 0.89 | BHMT (0.50) | GSRBHMTBHMT2NOS3NOS1 | |
| Methionine SCHEMBL11215180 | 0.89 | BHMT (0.50) | GSRBHMTBHMT2NOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2836832-A1 | EARLY TRIMESTER SCREENING FOR EARLY- AND LATE-ONSET PREECLAMPSIA | Wayne State University (US) | 2015-02-18 | — | — | EP | disclosed |
| WO-2013155458-A1 | EARLY TRIMESTER SCREENING FOR EARLY- AND LATE-ONSET PREECLAMPSIA | WAYNE STATE UNIVERSITY (US) | 2013-10-17 | — | — | WO | disclosed |