Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.53 |
| ▸ | SLC1A3 | P43003 | 6/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 6/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 7/20 | 0.38 |
| ▸ | LAP3 | P28838 | 3/20 | 0.34 |
| ▸ | GRIK1 | P39086 | 6/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.32 |
| ▸ | GRIK3 | Q13003 | 3/20 | 0.32 |
| ▸ | GRIK5 | Q16478 | 3/20 | 0.32 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.31 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Threonine SCHEMBL2765872 | 0.84 | SLC7A5 (0.39) | SLC7A5SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL442281 | 0.84 | SLC7A5 (0.30) | SLC7A5 | |
| Serine SCHEMBL5698241 | 0.82 | SLC7A5 (0.33) | SLC7A5SLC1A3SLC1A2SLC1A1GRIK1 | |
| SCHEMBL8439242 | 0.81 | SLC7A5 (0.44) | SLC7A5SLC1A3SLC1A2SLC1A1GRIK1 | |
| Leucine SCHEMBL15323598 | 0.80 | SLC7A5 (0.50) | SLC7A5SLC1A3SLC1A2SLC1A1GRIK1 | |
| Leucine SCHEMBL15323192 | 0.80 | SLC7A5 (0.62) | SLC7A5SLC1A3SLC1A2SLC1A1GRIK1 | |
| Leucine SCHEMBL15323189 | 0.80 | SLC7A5 (0.62) | SLC7A5SLC1A3SLC1A2SLC1A1GRIK1 | |
| Leucine SCHEMBL16348668 | 0.79 | SLC7A5 (0.40) | SLC7A5SLC1A3SLC1A2SLC1A1 | |
| Leucine SCHEMBL15323699 | 0.79 | SLC7A5 (0.72) | SLC7A5SLC1A3SLC1A2SLC1A1LAP3 | |
| Leucine SCHEMBL15323703 | 0.79 | SLC7A5 (0.72) | SLC7A5SLC1A3SLC1A2SLC1A1LAP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2836832-A1 | EARLY TRIMESTER SCREENING FOR EARLY- AND LATE-ONSET PREECLAMPSIA | Wayne State University (US) | 2015-02-18 | — | — | EP | disclosed |
| WO-2013155458-A1 | EARLY TRIMESTER SCREENING FOR EARLY- AND LATE-ONSET PREECLAMPSIA | WAYNE STATE UNIVERSITY (US) | 2013-10-17 | — | — | WO | disclosed |