SCHEMBL442281

SCHEMBL442281

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nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Threonine SCHEMBL2765872 0.93 SLC7A5 (0.39) SLC7A5
SCHEMBL1675353 0.85 SLC7A5 (0.33) SLC7A5
SCHEMBL599033 0.85 SLC7A5 (0.41) SLC7A5
SCHEMBL28679561 0.85 NAAA (0.33) SLC7A5
Leucine SCHEMBL15323191 0.84 SLC7A5 (0.53) SLC7A5
Serine SCHEMBL5698241 0.84 SLC7A5 (0.33) SLC7A5
Threonine SCHEMBL5073183 0.83 SLC7A5 (0.38) SLC7A5
Threonine SCHEMBL6856748 0.82 SLC7A5 (0.36) SLC7A5
SCHEMBL1537296 0.80 GRIN2D (0.33) SLC7A5
SCHEMBL186138 0.80 GRIN2D (0.33) SLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024141786-A2 MULTITARGET VACCINES AND THERAPEUTICS POPVAX PRIVATE LIMITED (IN) 2024-07-04 WO claimed
US-5252725-A α-1-antichymotrypsin, analogues and methods of production THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 1993-10-12 US claimed
WO-2024141784-A2 BROADLY PROTECTIVE BETACORONAVIRUS VACCINES AND COMPOSITIONS POPVAX PRIVATE LIMITED (IN) 2024-07-04 WO disclosed
WO-2024141786-A2 MULTITARGET VACCINES AND THERAPEUTICS POPVAX PRIVATE LIMITED (IN) 2024-07-04 WO disclosed
US-20210139897-A1 OLIGONUCLEOTIDE ANALOGUES HAVING MODIFIED INTERSUBUNIT LINKAGES AND/OR TERMINAL GROUPS SAREPTA THERAPEUTICS, INC. 2021-05-13 US disclosed
US-10760078-B2 Oligonucleotide analogues having modified intersubunit linkages and/or terminal groups SAREPTA THERAPEUTICS, INC. (US) 2020-09-01 US disclosed
US-20190218551-A1 OLIGONUCLEOTIDE ANALOGUES HAVING MODIFIED INTERSUBUNIT LINKAGES AND/OR TERMINAL GROUPS JPMORGAN CHASE BANK, N.A. AS ADMINISTRATIVE AGENT 2019-07-18 US disclosed
US-10202602-B2 Oligonucleotide analogues having modified intersubunit linkages and/or terminal groups SAREPTA THERAPEUTICS, INC. (US) 2019-02-12 US disclosed
US-20170198287-A1 OLIGONUCLEOTIDE ANALOGUES HAVING MODIFIED INTERSUBUNIT LINKAGES AND/OR TERMINAL GROUPS JPMORGAN CHASE BANK, N.A. AS ADMINISTRATIVE AGENT 2017-07-13 US disclosed
CN-106279715-A A kind of copper peptide Porous coordination polymer and its preparation method and application 武汉大学 2017-01-04 CN disclosed
US-9469664-B2 Oligonucleotide analogues having modified intersubunit linkages and/or terminal groups SAREPTA THERAPEUTICS, INC. (US) 2016-10-18 US disclosed
US-8779128-B2 Oligonucleotide analogues having modified intersubunit linkages and/or terminal groups SAREPTA THERAPEUTICS, INC. (US) 2014-07-15 US disclosed
EP-2638161-A1 ANTISENSE ANTIBACTERIAL COMPOUNDS AND METHODS Sarepta Therapeutics, Inc. (US) 2013-09-18 EP disclosed
EP-2576574-A2 OLIGONUCLEOTIDE ANALOGUES HAVING MODIFIED INTERSUBUNIT LINKAGES AND/OR TERMINAL GROUPS Sarepta Therapeutics, Inc. (US) 2013-04-10 EP disclosed
WO-2012064991-A1 ANTISENSE ANTIBACTERIAL COMPOUNDS AND METHODS AVI BIOPHARMA, INC. (US) 2012-05-18 WO disclosed
US-20120122769-A1 ANTISENSE ANTIBACTERIAL COMPOUNDS AND METHODS AVI BIOPHARMA, INC. (US) 2012-05-17 US disclosed
US-20120065169-A1 OLIGONUCLEOTIDE ANALOGUES HAVING MODIFIED INTERSUBUNIT LINKAGES AND/OR TERMINAL GROUPS JPMORGAN CHASE BANK, N.A. AS ADMINISTRATIVE AGENT 2012-03-15 US disclosed
WO-2011150408-A2 OLIGONUCLEOTIDE ANALOGUES HAVING MODIFIED INTERSUBUNIT LINKAGES AND/OR TERMINAL GROUPS AVI BIOPHARMA, INC. (US) 2011-12-01 WO disclosed
WO-2004080920-A1 HYDROPONIC PLANT NUTRIENT KIT AND METHOD OF USE ADVANCED NUTRIENTS LTD. (CA) 2004-09-23 WO disclosed
US-20030226753-A1 Capillaries electrophoresis, chromatography; intersecting channels; switching potentials RAMSEY J MICHAEL (US) 2003-12-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190218551-A1 OLIGONUCLEOTIDE ANALOGUES HAVING MODIFIED INTERSUBUNIT LINKAGES AND/OR TERMINAL GROUPS NSUN2, UPF1, RTCB SLC7A5 3950/4885
US-20120065169-A1 OLIGONUCLEOTIDE ANALOGUES HAVING MODIFIED INTERSUBUNIT LINKAGES AND/OR TERMINAL GROUPS NSUN2, UPF1, RTCB SLC7A5 3950/4885
US-20120122769-A1 ANTISENSE ANTIBACTERIAL COMPOUNDS AND METHODS RNGTT, SRRT, RNMT SLC7A5 335/4885
US-10202602-B2 Oligonucleotide analogues having modified intersubunit linkages and/or terminal groups NSUN2, RTCB, UPF1 SLC7A5 3989/4885
US-10760078-B2 Oligonucleotide analogues having modified intersubunit linkages and/or terminal groups NSUN2, UPF1, RTCB SLC7A5 3950/4885
US-20210139897-A1 OLIGONUCLEOTIDE ANALOGUES HAVING MODIFIED INTERSUBUNIT LINKAGES AND/OR TERMINAL GROUPS NSUN2, UPF1, RTCB SLC7A5 3950/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.