Threonine

Threonine

SCHEMBL2765872

C[C@@H](O)[C@H](N)C(=O)O.C[C@@H](O)[C@H](N)C(=O)OC(=O)CN

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 2/20 0.39
SLC1A3 P43003 1/20 0.34
SLC1A2 P43004 1/20 0.34
SLC1A1 P43005 1/20 0.34
USP2 O75604 1/20 0.32
SLCO1B1 Q9Y6L6 1/20 0.32
GABRR1 P24046 2/20 0.31
P2RY10 O00398 2/20 0.30
GPR174 Q9BXC1 2/20 0.30
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL442281 0.93 SLC7A5 (0.30) SLC7A5
Threonine SCHEMBL5073183 0.91 SLC7A5 (0.38) SLC7A5SLC1A3SLC1A2SLC1A1USP2
Threonine SCHEMBL6856748 0.90 SLC7A5 (0.36) SLC7A5SLC1A3SLC1A2SLC1A1USP2
SCHEMBL1675353 0.89 SLC7A5 (0.33) SLC7A5SLC1A3SLC1A2SLC1A1P2RY10
Serine SCHEMBL5698241 0.84 SLC7A5 (0.33) SLC7A5SLC1A3SLC1A2SLC1A1USP2
Leucine SCHEMBL15323191 0.84 SLC7A5 (0.53) SLC7A5SLC1A3SLC1A2SLC1A1
Threonine SCHEMBL6367180 0.81 METAP2 (0.35) SLC7A5
Threonine SCHEMBL2076958 0.79 NOS3 (0.37) SLC7A5SLC1A3SLC1A2SLC1A1P2RY10
SCHEMBL28679561 0.79 NAAA (0.33) SLC7A5
SCHEMBL599033 0.79 SLC7A5 (0.41) SLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4340592-A OLICOPEPTIDES FOR DIETARY PURPOSES ADIBI SIAMAK A 1982-07-20 US claimed
US-9458197-B2 Elastin digest compositions and methods utilizing same HUMAN MATRIX SCIENCES, LLC (US) 2016-10-04 US disclosed
US-20150004184-A1 ELASTIN DIGEST COMPOSITIONS AND METHODS UTILIZING SAME NULASTIN, INC. 2015-01-01 US disclosed
US-8828927-B2 Elastin digest compositions and methods utilizing same HUMAN MATRIX SCIENCES, LLC (US) 2014-09-09 US disclosed
US-20130295122-A1 ELASTIN DIGEST COMPOSITIONS AND METHODS UTILIZING SAME NULASTIN, INC. 2013-11-07 US disclosed
US-8461113-B2 Elastin digest compositions and methods utilizing same HUMAN MATRIX SCIENCES, LLC (US) 2013-06-11 US disclosed
US-7666829-B2 contains manganese chloride, manganese sulfate or manganese nitrate and ferric ammonium citrate or ferric chloride, for treating skin disorders; stimulating production of insoluble elastin, or deposition of collagen, fibroblasts; improve the appearance of scar; wrinkle resistance HUMAN MATRIX SCIENCES, LLC (US) 2010-02-23 US disclosed
US-20090281044-A1 ELASTIN DIGEST COMPOSITIONS AND METHODS UTILIZING SAME NULASTIN, INC. 2009-11-12 US disclosed