Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.34 |
| ▸ | BHMT | Q93088 | 2/20 | 0.34 |
| ▸ | BHMT2 | Q9H2M3 | 1/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.31 |
| ▸ | METAP1 | P53582 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Leucine SCHEMBL16348669 | 0.86 | SLC7A5 (0.46) | SLC7A5SLC1A3SLC1A2BHMTBHMT2 | |
| Threonine SCHEMBL6367180 | 0.86 | METAP2 (0.35) | SLC7A5BHMTBHMT2FOLH1METAP2 | |
| Leucine SCHEMBL27487105 | 0.86 | SLC7A5 (0.55) | SLC7A5SLC1A3SLC1A2BHMTBHMT2 | |
| Leucine SCHEMBL27814601 | 0.86 | SLC7A5 (0.55) | SLC7A5SLC1A3SLC1A2BHMTBHMT2 | |
| Leucine SCHEMBL15323685 | 0.85 | SLC7A5 (0.47) | SLC7A5SLC1A3SLC1A2BHMTBHMT2 | |
| Leucine SCHEMBL15322444 | 0.84 | SLC7A5 (0.53) | SLC7A5SLC1A3SLC1A2BHMTBHMT2 | |
| Leucine SCHEMBL15322442 | 0.84 | SLC7A5 (0.53) | SLC7A5SLC1A3SLC1A2BHMTBHMT2 | |
| Threonine SCHEMBL5073183 | 0.80 | SLC7A5 (0.38) | SLC7A5SLC1A3SLC1A2SLC1A1 | |
| Lysine SCHEMBL8860263 | 0.80 | GSR (0.50) | SLC7A5SLC1A3SLC1A2BHMTBHMT2 | |
| Lysine SCHEMBL8860269 | 0.80 | GSR (0.50) | SLC7A5SLC1A3SLC1A2BHMTBHMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8933193-B2 | Lantibiotics and uses thereof | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2015-01-13 | — | — | US | disclosed |
| US-20110305763-A1 | LANTIBIOTICS AND USES THEREOF | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2011-12-15 | — | — | US | disclosed |