Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19608784 | 0.83 | TDP1 (0.44) | PRKCAALDH1A1LMNATDP1AR | |
| SCHEMBL2160922 | 0.81 | PRKCA (0.36) | PRKCAALDH1A1LMNATDP1 | |
| SCHEMBL8843273 | 0.77 | ALDH1A1 (0.39) | PRKCAALDH1A1LMNA | |
| Acetamide SCHEMBL15324339 | 0.76 | PRKCA (0.50) | PRKCA | |
| SCHEMBL3387292 | 0.75 | CTSK (0.38) | PRKCALMNATDP1 | |
| SCHEMBL13356385 | 0.74 | PRKCA (0.46) | PRKCA | |
| SCHEMBL10977328 | 0.74 | PRKCA (0.42) | PRKCAALDH1A1LMNATDP1 | |
| SCHEMBL15902886 | 0.74 | PRKCA (0.51) | PRKCAALDH1A1LMNA | |
| SCHEMBL9055890 | 0.74 | TDP1 (0.37) | PRKCAALDH1A1LMNATDP1AR | |
| SCHEMBL3391427 | 0.72 | PRKCA (0.42) | PRKCAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2836833-A1 | PRENATAL SCREENING FOR DOWN SYNDROME AND TRISOMY 18 | Wayne State University (US) | 2015-02-18 | — | — | EP | disclosed |
| WO-2013155456-A1 | PRENATAL SCREENING FOR DOWN SYNDROME AND TRISOMY 18 | WAYNE STATE UNIVERSITY (US) | 2013-10-17 | — | — | WO | disclosed |