Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAUR | Q03405 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | PARP1 | P09874 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1042351 | 0.82 | PLAUR (0.54) | PLAURMEN1KMT2APARP1TRPV1 | |
| Bromide SCHEMBL5141524 | 0.81 | PLAUR (0.53) | PLAURMEN1KMT2APARP1TRPV1 | |
| SCHEMBL1038475 | 0.78 | PLAUR (0.50) | PLAURPARP1TRPV1 | |
| SCHEMBL3287778 | 0.76 | MEN1 (0.58) | MEN1KMT2APOLBTDP1GAA | |
| SCHEMBL30291834 | 0.76 | MEN1 (0.58) | MEN1KMT2APOLBTDP1GAA | |
| SCHEMBL30682553 | 0.73 | PLAUR (1.00) | PLAURMEN1KMT2APOLBTDP1 | |
| SCHEMBL1013125 | 0.73 | PARP1 (0.59) | MEN1KMT2APOLBTDP1GAA | |
| SCHEMBL6118216 | 0.73 | GAA (0.54) | MEN1KMT2APOLBTDP1GAA | |
| SCHEMBL9187595 | 0.73 | MAPT (0.54) | MEN1KMT2APOLBTDP1GAA | |
| SCHEMBL1897684 | 0.73 | PLAUR (1.00) | PLAURMEN1KMT2APOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013153539-A1 | TRICYCLIC COMPOUNDS AS TEC KINASE INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2013-10-17 | — | — | WO | disclosed |