SCHEMBL1042351

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	Bromide SCHEMBL5141524	0.98	PLAUR (0.53)	PLAURATRPARP1TNKSTNKS2
	SCHEMBL15323237	0.82	PLAUR (0.58)	PLAURPARP1MEN1KMT2AKDM4E
	SCHEMBL3237187	0.79	PARP1 (0.53)	PARP1TNKSTNKS2MEN1KMT2A
	SCHEMBL14222708	0.78	NUDT1 (0.51)	ATRMEN1KMT2APLAUNCF1
	SCHEMBL6081154	0.77	GRIN1 (0.45)	ATRPARP1TNKSTNKS2KMT2A
	SCHEMBL1038475	0.76	PLAUR (0.50)	PLAURPARP1TNKSTNKS2CYP2D6
	SCHEMBL4314003	0.74	ACHE (0.46)	ATRPARP1KMT2AKDM4ECYP1A2
	SCHEMBL13897695	0.73	DAO (0.45)	PLAURMEN1KMT2AKDM4EDAO
	SCHEMBL4629094	0.72	PARP1 (0.47)	PARP1
	SCHEMBL1043194	0.72	PLAUR (0.54)	PLAURPARP1TNKSTNKS2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.