SCHEMBL3287778

SCHEMBL3287778

Nc1nc2c(N)cccc2[nH]1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.58
KMT2A Q03164 2/20 0.58
GAA P10253 2/20 0.58
MAPT P10636 2/20 0.58
POLB P06746 1/20 0.58
TDP1 Q9NUW8 1/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
NUDT1 P36639 4/20 0.54
ALDH1A1 P00352 2/20 0.52
MASP2 O00187 1/20 0.52
AOC3 Q16853 1/20 0.52
CDK5 Q00535 7/20 0.47
CDK5R1 Q15078 7/20 0.47
CHEK1 O14757 1/20 0.45
ULK1 O75385 1/20 0.45
CDK7 P50613 1/20 0.45
PRKCE Q02156 1/20 0.45
CAMK2G Q13555 1/20 0.45
DYRK1A Q13627 1/20 0.45
RPS6KA1 Q15418 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30291834 1.00 MEN1 (0.58) MEN1KMT2AGAAMAPTPOLB
Benzimidazole SCHEMBL7255238 0.82 NUDT1 (0.49) MEN1KMT2AGAAMAPTPOLB
SCHEMBL9187595 0.79 MAPT (0.54) MEN1KMT2AGAAMAPTPOLB
SCHEMBL1013125 0.79 PARP1 (0.59) MEN1KMT2AGAAMAPTPOLB
SCHEMBL6118216 0.79 GAA (0.54) MEN1KMT2AGAAMAPTPOLB
SCHEMBL14222708 0.79 NUDT1 (0.51) MEN1KMT2AGAANUDT1ALDH1A1
SCHEMBL727228 0.79 MGAM (0.53) MEN1KMT2AGAANUDT1ALDH1A1
SCHEMBL17276083 0.79 NUDT1 (0.51) MEN1KMT2AGAAMAPTPOLB
SCHEMBL215756 0.79 NUDT1 (0.70) MEN1KMT2AGAANUDT1ALDH1A1
SCHEMBL17276019 0.79 NUDT1 (0.51) MEN1KMT2ANUDT1ALDH1A1MASP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 339 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122035842-A Nitrogen-containing spherical carbon powder and preparation method and application thereof 重庆锦添翼新能源科技有限公司 2026-05-15 CN claimed
CN-119798660-A Polyimide carbon molecular sieve membrane containing benzimidazole and preparation method and application thereof 浙江工业大学 2025-04-11 CN claimed
CN-119709104-A Synthesis method of high-performance polyimide binder with three-dimensional reticular structure 江西洪州职业学院 2025-03-28 CN claimed
CN-118925780-B Fe-N-C bifunctional catalyst and preparation method and application thereof 内蒙古工业大学 2025-02-18 CN claimed
CN-119433837-A PI nanofiber membrane for lithium battery and preparation method 天台智能制造研究院 2025-02-14 CN claimed
CN-119306669-A Benzimidazole diamine and polybenzimidazole imide as well as preparation methods and application thereof 中广核研究院有限公司 2025-01-14 CN claimed
CN-119074684-A Drug delivery nano vesicle based on self-activated T cell membrane, preparation method and application 重庆医科大学附属第一医院 2024-12-06 CN claimed
CN-119060537-A Self-lubricating wear-resistant polyphenylene sulfide-based composite material and preparation method thereof 江西聚真科技发展有限公司 2024-12-03 CN claimed
CN-118925780-A Fe-N-C bifunctional catalyst and preparation method and application thereof 内蒙古工业大学 2024-11-12 CN claimed
CN-118873559-A Macrophage-oncolytic virus coupling system, preparation method and application thereof in preparing antitumor drugs 国科温州研究院(温州生物材料与工程研究所) 2024-11-01 CN claimed
CN-101973986-B Benzimidazole structure-containing diamine benzoxazine intermediate and preparation method thereof UNIV SICHUAN 2012-06-27 CN claimed
CN-102031082-A Benzimidazole diamine curing type epoxy adhesive and preparation method thereof UNIV DONGHUA 2011-04-27 CN claimed
CN-101973986-A Benzimidazole structure-containing diamine benzoxazine intermediate and preparation method thereof UNIV SICHUAN 2011-02-16 CN claimed
CN-1976977-B Benzimidazole diamine-based polyetherimide compositions and methods of making the same GEN ELECTRIC 2010-05-26 CN claimed
CN-1976977-A Benzimidazole diamine-based polyetherimide compositions and methods of making the same GEN ELECTRIC (US) 2007-06-06 CN claimed
US-7071282-B2 Benzimidazole diamine-based polyetherimide compositions and methods for making them GENERAL ELECTRIC COMPANY (US) 2006-07-04 US claimed
EP-1633802-A1 BENZIMIDAZOLE DIAMINE-BASED POLYETHERIMIDE COMPOSITIONS AND METHODS FOR MAKING THEM GENERAL ELECTRIC COMPANY (US) 2006-03-15 EP claimed
WO-2004108797-A1 BENZIMIDAZOLE DIAMINE-BASED POLYETHERIMIDE COMPOSITIONS AND METHODS FOR MAKING THEM GENERAL ELECTRIC COMPANY (US) 2004-12-16 WO claimed
US-20040249117-A1 Benzimidazole diamine-based polyetherimide compositions and methods for making them GENERAL ELECTRIC COMPANY 2004-12-09 US claimed
EP-0669380-B1 Process for the preparation of azo dyes CIBA SC HOLDING AG (CH) 2001-03-28 EP claimed