Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7848812 | 0.76 | — | — | |
| SCHEMBL18060 | 0.74 | — | — | |
| SCHEMBL1035408 | 0.74 | NOS3 (0.36) | NOS3NOS1NOS2 | |
| Ammonia Solution, Strong SCHEMBL3055814 | 0.71 | — | — | |
| SCHEMBL24229293 | 0.69 | ESR2 (0.32) | NOS3NOS1NOS2 | |
| SCHEMBL569231 | 0.69 | TRIM24 (0.33) | NOS3NOS1NOS2 | |
| SCHEMBL163531 | 0.67 | — | — | |
| SCHEMBL15323288 | 0.66 | NOS3 (0.32) | NOS3NOS1NOS2 | |
| SCHEMBL8134925 | 0.65 | — | — | |
| SCHEMBL12086405 | 0.64 | ALDH1A1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013153535-A1 | TRICYCLIC COMPOUNDS AS mPGES-1 INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2013-10-17 | — | — | WO | claimed |
| WO-2013153535-A1 | TRICYCLIC COMPOUNDS AS mPGES-1 INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2013-10-17 | — | — | WO | disclosed |