Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 2/20 | 0.33 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28247829 | 0.91 | TRIM24 (0.39) | TRIM24TRIM33ESR2NOS3NOS1 | |
| SCHEMBL29281259 | 0.84 | NOS3 (0.39) | NOS3NOS1NOS2 | |
| SCHEMBL30342216 | 0.84 | — | — | |
| SCHEMBL13766339 | 0.83 | TRIM24 (0.33) | TRIM24TRIM33ESR2ALDH1A1 | |
| SCHEMBL28185295 | 0.82 | CYP1A2 (0.45) | ESR2 | |
| SCHEMBL12326589 | 0.79 | CA1 (0.31) | TRIM24TRIM33ESR2ALDH1A1 | |
| SCHEMBL12326782 | 0.79 | TRIM24 (0.30) | TRIM24TRIM33ESR2 | |
| SCHEMBL26099934 | 0.79 | TRIM24 (0.30) | TRIM24TRIM33ESR2 | |
| SCHEMBL14285871 | 0.75 | PIM1 (0.32) | — | |
| SCHEMBL14421783 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 512 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117645533-B | Synthesis method of 4- (trifluoromethyl) cyclohexanone | 泰州精英化成医药科技有限公司 | 2024-10-11 | — | — | CN | claimed |
| CN-117645533-A | Synthesis method of 4- (trifluoromethyl) cyclohexanone | 泰州精英化成医药科技有限公司 | 2024-03-05 | — | — | CN | claimed |
| CN-113789527-B | Electrochemical synthesis method of aromatic amine | 四川大学 | 2023-02-28 | — | — | CN | claimed |
| CN-113789527-A | Electrochemical synthesis method of aromatic amine | 四川大学 | 2021-12-14 | — | — | CN | claimed |
| EP-4746861-A1 | BIS(PHENYLMETHYLENE)CYCLOALKANONES AND THEIR HETEROCYCLIC ANALOGUES AND THEIR USE AS MEDICAMENTS, FOR THE TREATMENT OR PREVENTION OF PROTEINOPATHIES | Ustav Organicke Chemie a Biochemie AV CR v.v.i. (CZ) | 2026-05-27 | — | — | EP | disclosed |
| EP-4680336-A1 | AMIDE DERIVATIVES FOR INHIBITING NLRP3 AND USES THEREOF | Ventus Therapeutics U.S., Inc. (US) | 2026-01-21 | — | — | EP | disclosed |
| US-12528798-B2 | Compound for crop protectant | LG CHEM, LTD. (KR) | 2026-01-20 | — | — | US | disclosed |
| US-20260007684-A1 | AMIDE DERIVATIVES FOR INHIBITING NLRP3 AND USES THEREOF | VENTUS THERAPEUTICS U S INC (US) | 2026-01-08 | — | — | US | disclosed |
| EP-4663640-A1 | XANTHINE COMPOUND AND USE THEREOF | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2025-12-17 | — | — | EP | disclosed |
| US-12441679-B2 | Acrylamide-substituted indane compounds and therapeutic use thereof | SANOFI (FR) | 2025-10-14 | — | — | US | disclosed |
| EP-4626860-A1 | FUSED PYRROLYL-SULFONAMIDE COMPOUNDS | ReWind Therapeutics NV (BE) | 2025-10-08 | — | — | EP | disclosed |
| US-12358887-B2 | IKAROS Zinc Finger Family degraders and uses thereof | GILEAD SCIENCES, INC. (US) | 2025-07-15 | — | — | US | disclosed |
| US-20030078460-A1 | Process for producing alpha, alpha-difluorocycloalkane compound | MITSUI CHEMICALS, INC. (JP) | 2003-04-24 | — | — | US | disclosed |
| EP-1220841-A2 | TRIFLUOROMETHYL-SUBSTITUTED SPIROCYCLIC KETOENOLS | Bayer Aktiengesellschaft (DE) | 2002-07-10 | — | — | EP | disclosed |
| EP-0921125-B1 | 1,3,8-Triazaspiro[4,5]decan-4-on derivatives | HOFFMANN LA ROCHE (CH) | 2002-01-30 | — | — | EP | disclosed |
| WO-2001023354-A2 | TRIFLUOROMETHYL-SUBSTITUTED SPIROCYCLIC KETOENOLS AND USE THEREOF AS PESTICIDES AND HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-04-05 | — | — | WO | disclosed |
| US-6043366-A | USEFUL IN TREATING DISORDERS INVOLVING THE ORPHANIN FQ(A SEVENTEEN AMINO ACID LONG PEPTIDE) RECEPTOR. | HOFFMAN-LA ROCHE INC. (US) | 2000-03-28 | — | — | US | disclosed |
| CN-1222521-A | 1,3,8-triaza-spiro [4,5] decan-4-on derivatives | HOFFMANN LA ROCHE (CH) | 1999-07-14 | — | — | CN | disclosed |
| EP-0921125-A1 | 1,3,8-Triaza-spiro 4,5 decan-4-on derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1999-06-09 | — | — | EP | disclosed |
| WO-1994027972-A1 | SUBSTITUTED PYRAZOLINES HAVING INSECTICIDAL AND ACARICIDAL ACTIVITY | SCHERING AKTIENGESELLSCHAFT (DE) | 1994-12-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12358887-B2 | IKAROS Zinc Finger Family degraders and uses thereof | IKZF2, IKZF1, IKZF3 | TRIM24 241/4885TRIM33 61/4885ESR2 1037/4885 |
| US-12441679-B2 | Acrylamide-substituted indane compounds and therapeutic use thereof | IDH2, INA, IDH3A | TRIM24 4008/4885TRIM33 3535/4885ESR2 955/4885 |
| US-12528798-B2 | Compound for crop protectant | CBR1, CBR3, GSTO1 | TRIM24 2344/4885TRIM33 3028/4885ESR2 2003/4885 |
| US-20260007684-A1 | AMIDE DERIVATIVES FOR INHIBITING NLRP3 AND USES THEREOF | NOD1, NLRP3, NOD2 | TRIM24 3246/4885TRIM33 3148/4885ESR2 1609/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.