Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.53 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.44 |
| ▸ | BHMT | Q93088 | 4/20 | 0.43 |
| ▸ | BHMT2 | Q9H2M3 | 1/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.40 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | METAP1 | P53582 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 2/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | MARS1 | P56192 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Leucine SCHEMBL9714739 | 0.89 | SLC7A5 (0.67) | SLC7A5SLC1A3SLC1A2BHMTBHMT2 | |
| Leucine SCHEMBL1352746 | 0.89 | SLC7A5 (0.67) | SLC7A5SLC1A3SLC1A2BHMTBHMT2 | |
| Leucine SCHEMBL1352748 | 0.89 | SLC7A5 (0.67) | SLC7A5SLC1A3SLC1A2BHMTBHMT2 | |
| Leucine SCHEMBL23924432 | 0.89 | SLC7A5 (0.67) | SLC7A5SLC1A3SLC1A2BHMTBHMT2 | |
| Leucine SCHEMBL15323407 | 0.88 | SLC7A5 (0.64) | SLC7A5SLC1A3SLC1A2BHMTBHMT2 | |
| Leucine SCHEMBL15323403 | 0.88 | SLC7A5 (0.64) | SLC7A5SLC1A3SLC1A2BHMTBHMT2 | |
| Leucine SCHEMBL8497051 | 0.86 | SLC7A5 (0.62) | SLC7A5SLC1A3SLC1A2BHMTBHMT2 | |
| Leucine SCHEMBL8497054 | 0.86 | SLC7A5 (0.62) | SLC7A5SLC1A3SLC1A2BHMTBHMT2 | |
| SCHEMBL108560 | 0.84 | MARS1 (0.44) | RNPEPMETAP2METAP1MARS1 | |
| SCHEMBL108559 | 0.84 | MARS1 (0.44) | RNPEPMETAP2METAP1MARS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2836832-A1 | EARLY TRIMESTER SCREENING FOR EARLY- AND LATE-ONSET PREECLAMPSIA | Wayne State University (US) | 2015-02-18 | — | — | EP | disclosed |
| WO-2013155458-A1 | EARLY TRIMESTER SCREENING FOR EARLY- AND LATE-ONSET PREECLAMPSIA | WAYNE STATE UNIVERSITY (US) | 2013-10-17 | — | — | WO | disclosed |