SCHEMBL108559

SCHEMBL108559

COC(=O)C(N)CCSC

nearest known ligand 0.61

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MARS1 P56192 6/20 0.44
METAP2 P50579 1/20 0.43
METAP1 P53582 1/20 0.43
ALDH1A1 P00352 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.41
RNPEP Q9H4A4 1/20 0.41
CYP2C9 P11712 1/20 0.40
GAA P10253 1/20 0.39
ANPEP P15144 1/20 0.39
ENPEP Q07075 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL108560 1.00 MARS1 (0.44) MARS1METAP2METAP1ALDH1A1L3MBTL1
SCHEMBL3089957 1.00 MARS1 (0.44) MARS1METAP2METAP1ALDH1A1L3MBTL1
Ammonia Solution, Strong SCHEMBL9081566 0.98 MARS1 (0.43) MARS1METAP2METAP1ALDH1A1L3MBTL1
Hydrochloric Acid SCHEMBL3089952 0.98 MARS1 (0.43) MARS1METAP2METAP1ALDH1A1L3MBTL1
Hydrochloric Acid SCHEMBL200899 0.98 MARS1 (0.43) MARS1METAP2METAP1ALDH1A1L3MBTL1
Hydrogen Sulfide SCHEMBL9171273 0.98 MARS1 (0.43) MARS1METAP2METAP1ALDH1A1L3MBTL1
Hydrochloric Acid SCHEMBL200898 0.98 MARS1 (0.43) MARS1METAP2METAP1ALDH1A1L3MBTL1
Sulfur Dioxide SCHEMBL28722439 0.96 MARS1 (0.42) MARS1METAP2METAP1ALDH1A1L3MBTL1
SCHEMBL6552211 0.94 MARS1 (0.41) MARS1METAP2METAP1ALDH1A1L3MBTL1
SCHEMBL28363177 0.93 ALDH1A1 (0.41) MARS1METAP2METAP1ALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 569 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115304516-A Compounds with unconventional chromophores, their preparation and use 四川大学 2022-11-08 CN claimed
CN-112920118-A Genipin amino acid derivative and preparation method and application thereof 合肥华方医药科技有限公司 2021-06-08 CN claimed
US-20200116730-A1 METHOD AND SYSTEM FOR THE NON-DESTRUCTIVE IN OVO DETERMINATION OF FOWL GENDER IN OVO B.V. (NL) 2020-04-16 US claimed
CN-109897293-A A kind of ultra-low thermal conductivity accessories for windows and doors moulded insulation 天津格亚德新材料科技有限公司 2019-06-18 CN claimed
CN-109628544-A A kind of lipase is splitting the application in N- acetyl-DL- methionine methyl ester 浙江工业大学 2019-04-16 CN claimed
EP-3465222-A2 METHOD AND SYSTEM FOR THE NON-DESTRUCTIVE IN OVO DETERMINATION OF FOWL GENDER In Ovo B.V. (NL) 2019-04-10 EP claimed
US-10144914-B2 Modified substrates for protection of peptide-immobilized surfaces from gamma radiation degradation CORNING INCORPORATED (US) 2018-12-04 US claimed
CN-104628714-B Ester derivant of dabigatran and its production and use 沈阳工业大学 2018-02-16 CN claimed
WO-2017204636-A2 METHOD AND SYSTEM FOR THE NON-DESTRUCTIVE IN OVO DETERMINATION OF FOWL GENDER IN OVO B.V. (NL) 2017-11-30 WO claimed
CN-105349609-A Method for improving chiral resolution performance of lipase on amino-acid ester in organic phase UNIV ZHEJIANG SCIENCE & TECH 2016-02-24 CN claimed
EP-0952842-A2 A METHOD OF TREATING CANCER Merck & Co., Inc. (US) 1999-11-03 EP claimed
US-5977280-A Terminating post cure with amino acid esters DOW CORNING CORPORATION (US) 1999-11-02 US claimed
EP-0915123-A1 Terminating post cure of silicone elastomers with amino acid esters DOW CORNING CORPORATION (US) 1999-05-12 EP claimed
WO-1998045266-A1 3-AMINOPYRIDINE DERIVATIVES FOR TREATMENT OF INFLAMMATORY AND MALIGNANT DISEASES FERRING B.V. (NL) 1998-10-15 WO claimed
WO-1997038664-A2 A METHOD OF TREATING CANCER MERCK & CO., INC. (US) 1997-10-23 WO claimed
EP-0783518-A1 INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE MERCK & CO. INC. (US) 1997-07-16 EP claimed
EP-0783517-A2 THIOL-FREE INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE MERCK & CO. INC. (US) 1997-07-16 EP claimed
US-5136050-A Process for resolving amino acids using substituted lactones ROUSSEL UCLAF (FR) 1992-08-04 US claimed
US-4782104-A POLYACRYLAMIDE STABILIZED WITH METHIONINE MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1988-11-01 US claimed
EP-0030505-B1 LACTONES SUBSTITUTED BY AN AMINO-ACID RESIDUE, THEIR PREPARATION AND THEIR USE IN THE SEPARATION OF SAID LACTONES OR AMINO ACIDS ROUSSEL-UCLAF (FR) 1985-07-24 EP claimed