SCHEMBL108560

SCHEMBL108560

COC(=O)[C@@H](N)CCSC

nearest known ligand 0.61

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MARS1 P56192 6/20 0.44
METAP2 P50579 1/20 0.43
METAP1 P53582 1/20 0.43
ALDH1A1 P00352 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.41
RNPEP Q9H4A4 1/20 0.41
CYP2C9 P11712 1/20 0.40
GAA P10253 1/20 0.39
ANPEP P15144 1/20 0.39
ENPEP Q07075 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3089957 1.00 MARS1 (0.44) MARS1METAP2METAP1ALDH1A1L3MBTL1
SCHEMBL108559 1.00 MARS1 (0.44) MARS1METAP2METAP1ALDH1A1L3MBTL1
Ammonia Solution, Strong SCHEMBL9081566 0.98 MARS1 (0.43) MARS1METAP2METAP1ALDH1A1L3MBTL1
Hydrochloric Acid SCHEMBL3089952 0.98 MARS1 (0.43) MARS1METAP2METAP1ALDH1A1L3MBTL1
Hydrochloric Acid SCHEMBL200899 0.98 MARS1 (0.43) MARS1METAP2METAP1ALDH1A1L3MBTL1
Hydrogen Sulfide SCHEMBL9171273 0.98 MARS1 (0.43) MARS1METAP2METAP1ALDH1A1L3MBTL1
Hydrochloric Acid SCHEMBL200898 0.98 MARS1 (0.43) MARS1METAP2METAP1ALDH1A1L3MBTL1
Sulfur Dioxide SCHEMBL28722439 0.96 MARS1 (0.42) MARS1METAP2METAP1ALDH1A1L3MBTL1
SCHEMBL6552211 0.94 MARS1 (0.41) MARS1METAP2METAP1ALDH1A1L3MBTL1
SCHEMBL28363177 0.93 ALDH1A1 (0.41) MARS1METAP2METAP1ALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1939 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3967714-B1 VINYL ALCOHOL-AMINO ACID ESTER COPOLYMER, THEIR PREPARATION AND USES SEKISUI CHEMICAL CO LTD (JP) 2026-01-07 EP claimed
CN-119569652-A 2,2 '-Biquinoline-4, 4' -dicarboxylic acid aliphatic amino acid derivative, preparation and application thereof 武汉大学人民医院(湖北省人民医院) 2025-03-07 CN claimed
WO-2025047832-A1 SKIN COSMETIC COMPOSITION CONTAINING BOTRYOCOCCENE AS ACTIVE INGREDIENT フィコケミー株式会社 2025-03-06 WO claimed
CN-119409587-A Amino acid derivative of 2,2 '-binaphthyl-6, 6' -dicarboxylic acid, and preparation method and application thereof 武汉大学人民医院(湖北省人民医院) 2025-02-11 CN claimed
CN-119409588-A Caffeoyl amino acid methyl ester derivative and preparation method and application thereof 西北大学 2025-02-11 CN claimed
CN-119375485-A Method for improving protein methylation modification identification analysis 中国科学院大连化学物理研究所 2025-01-28 CN claimed
CN-118743985-B Solid waste-based modularized constructed wetland filler 皖创环保股份有限公司 2024-11-12 CN claimed
CN-118743985-A Novel solid waste-based modularized constructed wetland filler 皖创环保股份有限公司 2024-10-08 CN claimed
CN-118459369-A Synthetic method of N-Boc-vinyl glycine methyl ester and isomer thereof 成都师范学院 2024-08-09 CN claimed
CN-118290360-A Synthetic method of organic light response probe HBT-CN based on ESIPT effect, obtained probe and application thereof 临沂大学 2024-07-05 CN claimed
EP-0837875-A2 INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE Merck & Co., Inc. (US) 1998-04-29 EP claimed
WO-1997038664-A2 A METHOD OF TREATING CANCER MERCK & CO., INC. (US) 1997-10-23 WO claimed
EP-0783518-A1 INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE MERCK & CO. INC. (US) 1997-07-16 EP claimed
EP-0783517-A2 THIOL-FREE INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE MERCK & CO. INC. (US) 1997-07-16 EP claimed
WO-1996034010-A2 INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE MERCK & CO., INC. (US) 1996-10-31 WO claimed
US-5136050-A Process for resolving amino acids using substituted lactones ROUSSEL UCLAF (FR) 1992-08-04 US claimed
US-4782104-A POLYACRYLAMIDE STABILIZED WITH METHIONINE MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1988-11-01 US claimed
EP-0030505-B1 LACTONES SUBSTITUTED BY AN AMINO-ACID RESIDUE, THEIR PREPARATION AND THEIR USE IN THE SEPARATION OF SAID LACTONES OR AMINO ACIDS ROUSSEL-UCLAF (FR) 1985-07-24 EP claimed
EP-0025141-A1 Process for the production of 1-amino-cyclopropane-carboxylic acid and its derivatives BAYER AG (DE) 1981-03-18 EP claimed
US-3952115-A Fortification of foodstuffs with N-acyl derivatives of sulfur-containing L-amino acid esters THE PROCTER & GAMBLE COMPANY (US) 1976-04-20 US claimed