⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29114294 | 0.98 | TDP1 (0.65) | — | |
| SCHEMBL11847300 | 0.98 | TDP1 (0.65) | — | |
| SCHEMBL11835401 | 0.98 | TDP1 (0.65) | — | |
| SCHEMBL4660182 | 0.98 | TDP1 (0.65) | — | |
| SCHEMBL1865029 | 0.92 | — | — | |
| SCHEMBL15615683 | 0.82 | CES2 (0.46) | — | |
| SCHEMBL1085613 | 0.81 | — | — | |
| SCHEMBL9504312 | 0.80 | CES2 (0.50) | — | |
| SCHEMBL11441143 | 0.80 | CES2 (0.50) | — | |
| SCHEMBL3683268 | 0.80 | CES2 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10653709-B2 | Methods of folding a graft copolymer with dual anticancer drugs and related applications | NORTH CAROLINA STATE UNIVERSITY (US) | 2020-05-19 | — | — | US | claimed |
| US-20170080098-A1 | METHODS OF FOLDING A GRAFT COPOLYMER WITH DUAL ANTICANCER DRUGS AND RELATED APPLICATIONS | NORTH CAROLINA STATE UNIVERSITY (US) | 2017-03-23 | — | — | US | claimed |
| WO-2015179402-A1 | METHODS OF FOLDING A GRAFT COPOLYMER WITH DUAL ANTICANCER DRUGS AND RELATED APPLICATIONS | NORTH CAROLINA STATE UNIVERSITY (US) | 2015-11-26 | — | — | WO | claimed |
| JP-2006522140-A | — | — | 2006-09-28 | — | — | JP | claimed |
| EP-1608380-A2 | POLYMERIC DRUG AGENTS FOR THE TREATMENT OF FIBROTIC DISORDERS | Vectramed, Inc. (US) | 2005-12-28 | — | — | EP | claimed |
| WO-2004089311-A2 | POLYMERIC DRUG AGENTS FOR THE TREATMENT OF FIBROTIC DISORDERS | VECTRAMED, INC. (US) | 2004-10-21 | — | — | WO | claimed |
| EP-0153127-B1 | N-ARYL-3-ARYL-4,5-DIHYDRO-1H-PYRAZOLE-1-CARBOXAMIDES, PROCESSES FOR THEIR PRODUCTION, INSECTICIDAL COMPOSITIONS CONTAINING THEM AND METHODS FOR COMBATTING INSECTS | ROHM AND HAAS COMPANY (US) | 1991-04-03 | — | — | EP | claimed |
| EP-0153127-A2 | N-aryl-3-aryl-4,5-dihydro-1H-pyrazole-1-carboxamides, processes for their production, insecticidal compositions containing them and methods for combatting insects | ROHM AND HAAS COMPANY (US) | 1985-08-28 | — | — | EP | claimed |
| US-10653709-B2 | Methods of folding a graft copolymer with dual anticancer drugs and related applications | NORTH CAROLINA STATE UNIVERSITY (US) | 2020-05-19 | — | — | US | disclosed |
| US-20170080098-A1 | METHODS OF FOLDING A GRAFT COPOLYMER WITH DUAL ANTICANCER DRUGS AND RELATED APPLICATIONS | NORTH CAROLINA STATE UNIVERSITY (US) | 2017-03-23 | — | — | US | disclosed |
| WO-2015179402-A1 | METHODS OF FOLDING A GRAFT COPOLYMER WITH DUAL ANTICANCER DRUGS AND RELATED APPLICATIONS | NORTH CAROLINA STATE UNIVERSITY (US) | 2015-11-26 | — | — | WO | disclosed |
| US-8518885-B2 | Heterocyclic peptide ketoamides | GEORGIA TECH RESEARCH CORPORATION (US) | 2013-08-27 | — | — | US | disclosed |
| US-8013014-B2 | Aza-peptide epoxides | GEORGIA TECH RESEARCH CORPORATION (US) | 2011-09-06 | — | — | US | disclosed |
| US-20110053858-A1 | HETEROCYCLIC PEPTIDE KETOAMIDES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-03-03 | — | — | US | disclosed |
| US-4663341-A | Insecticidal n-aryl-3-aryl-4,5-dihydro-1h-pyrazole-1-carboxamides | ROHM AND HAAS COMPANY (US) | 1987-05-05 | — | — | US | disclosed |
| EP-0153127-A2 | N-aryl-3-aryl-4,5-dihydro-1H-pyrazole-1-carboxamides, processes for their production, insecticidal compositions containing them and methods for combatting insects | ROHM AND HAAS COMPANY (US) | 1985-08-28 | — | — | EP | disclosed |
| EP-0150974-A2 | Novel sulfonamides derived from substituted 2-amino-1,2,4-triazolo(1,5-a)pyrimidines and compositions and methods of controlling undesired vegetation | THE DOW CHEMICAL COMPANY (US) | 1985-08-07 | — | — | EP | disclosed |
| EP-0142152-A2 | Novel substituted 1,2,4-triazolo- [1,5-a] pyrimidine-2-sulfonamides and compositions and methods of controlling undesired vegetation and suppressing the nitrification of ammonium nitrogen in soil | THE DOW CHEMICAL COMPANY (US) | 1985-05-22 | — | — | EP | disclosed |
| US-4157344-A | REACTING PHENOLS WITH A PERHALOMETHANE AND HYDROGEN FLUORIDE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-06-05 | — | — | US | disclosed |
| US-3975538-A | O-ALKOXYCARBONYL-2-ALKOXY-1-NAPHTHOHYDROXAMATES | TAKEDA CHEMICAL INDUSTRIES, INC. (JA) | 1976-08-17 | — | — | US | disclosed |