Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CES2 | O00748 | 6/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | GMNN | O75496 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 3/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 7/20 | 0.42 |
| ▸ | FAAH | O00519 | 4/20 | 0.42 |
| ▸ | PLA2G6 | O60733 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29114294 | 1.00 | TDP1 (0.65) | TDP1ALDH1A1TSHRCES2TP53 | |
| SCHEMBL11847300 | 1.00 | TDP1 (0.65) | TDP1ALDH1A1TSHRCES2TP53 | |
| SCHEMBL11835401 | 1.00 | TDP1 (0.65) | TDP1ALDH1A1TSHRCES2TP53 | |
| SCHEMBL1532349 | 0.98 | — | — | |
| SCHEMBL1865029 | 0.90 | — | — | |
| SCHEMBL9504312 | 0.83 | CES2 (0.50) | TDP1ALDH1A1TSHRCES2TP53 | |
| SCHEMBL11441143 | 0.83 | CES2 (0.50) | TDP1ALDH1A1TSHRCES2TP53 | |
| SCHEMBL7804794 | 0.83 | CES2 (0.50) | TDP1ALDH1A1TSHRCES2TP53 | |
| SCHEMBL3683268 | 0.83 | CES2 (0.50) | TDP1ALDH1A1TSHRCES2TP53 | |
| Methane SCHEMBL3725723 | 0.81 | CES2 (0.48) | TDP1ALDH1A1TSHRCES2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117832456-A | Preparation method of rare earth doped amorphous carbon coated silicon-carbon composite material | 云南坤天新能源有限公司 | 2024-04-05 | — | — | CN | claimed |
| CN-117832456-A | Preparation method of rare earth doped amorphous carbon coated silicon-carbon composite material | 云南坤天新能源有限公司 | 2024-04-05 | — | — | CN | disclosed |
| EP-1255742-B1 | 2-THIO-4H-3,1-BENZOXAZIN-4-ONE DERIVATIVES FOR USE AS ENZYME INHIBITORS | ALIZYME THERAPEUTICS LTD (GB) | 2008-12-17 | — | — | EP | disclosed |
| EP-1255742-B1 | 2-THIO-4H-3,1-BENZOXAZIN-4-ONE DERIVATIVES FOR USE AS ENZYME INHIBITORS | ALIZYME THERAPEUTICS LTD (GB) | 2008-12-17 | — | — | EP | disclosed |
| US-7270801-B2 | Fluorogenic or fluorescent reporter molecules and their applications for whole-cell fluorescence screening assays for caspases and other enzymes and the use thereof | CYTOVIA, INC. (US) | 2007-09-18 | — | — | US | disclosed |
| US-6916808-B2 | 2-thio-4h-3, 1-benzoxazin-4-one derivatives for use as enzyme inhibitors | ALIZYME THERAPEUTICS LIMITED (GB) | 2005-07-12 | — | — | US | disclosed |
| EP-1026988-A4 | NOVEL FLUORESCENT REPORTER MOLECULES AND THEIR APPLICATIONS INCLUDING ASSAYS FOR CASPASES | CYTOVIA INC (US) | 2005-03-30 | — | — | EP | disclosed |
| US-20040191844-A1 | Novel fluorogenic or fluorescent reporter molecules and their applications for whole-cell fluorescence screening assays for caspases and other enzymes and the use thereof | CYTOVIA, INC. (US) | 2004-09-30 | — | — | US | disclosed |
| US-6759207-B2 | REPORTER COMPOUND FOR USE IN THE DIAGNOSIS, DETECTION AND TREATMENT OF CANCER | CYTOVIA, INC. | 2004-07-06 | — | — | US | disclosed |
| US-20030176429-A1 | 2-thio-4h-3,1-benzoxazin-4-one derivatives for use as enzyme inhibitors | NORGINE B.V. (NL) | 2003-09-18 | — | — | US | disclosed |
| WO-2001053278-A1 | 2-THIO-4H-3,1-BENZOXAZIN-4-ONE DERIVATIVES FOR USE AS ENZYME INHIBITORS | ALIZYME THERAPEUTICS LIMITED (GB) | 2001-07-26 | — | — | WO | disclosed |
| EP-1026988-A1 | NOVEL FLUORESCENT REPORTER MOLECULES AND THEIR APPLICATIONS INCLUDING ASSAYS FOR CASPASES | Cytovia, Inc. (US) | 2000-08-16 | — | — | EP | disclosed |
| WO-1999018856-A1 | NOVEL FLUORESCENT REPORTER MOLECULES AND THEIR APPLICATIONS INCLUDING ASSAYS FOR CASPASES | CYTOVIA, INC. (US) | 1999-04-22 | — | — | WO | disclosed |
| US-5362708-A | 6-Chloro-3-/p-fluorophenyl/pyridazin-4-yl S-octyl thiocarbonate | AGROLINZ AGRARCHEMIKALIEN GMBH (AT) | 1994-11-08 | — | — | US | disclosed |
| US-4820856-A | Process for the production of alkyl thiochloroformates | SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) | 1989-04-11 | — | — | US | disclosed |
| EP-0068592-B1 | NOVEL CARBAMATE DERIVATIVES | THE PROCTER & GAMBLE COMPANY (US) | 1984-10-17 | — | — | EP | disclosed |
| US-4443473-A | ANALGESICS, ANTIALLERGENS | THE PROCTER & GAMBLE COMPANY (US) | 1984-04-17 | — | — | US | disclosed |
| US-4400329-A | Process for the manufacture of thiochlorformates | SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) | 1983-08-23 | — | — | US | disclosed |
| EP-0068592-A1 | Novel carbamate derivatives | THE PROCTER & GAMBLE COMPANY (US) | 1983-01-05 | — | — | EP | disclosed |
| US-3975538-A | O-ALKOXYCARBONYL-2-ALKOXY-1-NAPHTHOHYDROXAMATES | TAKEDA CHEMICAL INDUSTRIES, INC. (JA) | 1976-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030176429-A1 | 2-thio-4h-3,1-benzoxazin-4-one derivatives for use as enzyme inhibitors | CYP4X1, CES1, CYP4B1 | TDP1 860/4885ALDH1A1 102/4885TSHR 851/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.