Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LDHA | P00338 | 1/20 | 0.31 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Deaminohydroxyvaline SCHEMBL15323262 | 0.98 | PDE4A (0.34) | PDE4AALDH1A1LDHASRRLMNA | |
| Malonic Acid SCHEMBL15322924 | 0.87 | LMNA (0.41) | ALDH1A1LDHASRRLMNAOR51E2 | |
| Malonic Acid SCHEMBL15323828 | 0.83 | LMNA (0.45) | PDE4AALDH1A1LDHASRRLMNA | |
| Succinic Acid SCHEMBL15323337 | 0.82 | EGLN1 (0.36) | ALDH1A1LDHASRRLMNA | |
| Deaminohydroxyvaline SCHEMBL15324660 | 0.80 | GPR84 (0.31) | — | |
| Malonic Acid SCHEMBL15324318 | 0.80 | LDHA (0.35) | ALDH1A1LDHASRRLMNA | |
| Deaminohydroxyvaline SCHEMBL15324671 | 0.79 | GPR84 (0.40) | PDE4AOR51E2TSHR | |
| Malonic Acid SCHEMBL15323090 | 0.78 | LDHA (0.36) | ALDH1A1LDHASRRLMNAOR51E2 | |
| Succinic Acid SCHEMBL15323882 | 0.77 | EGLN1 (0.39) | ALDH1A1LDHASRRLMNAOR51E2 | |
| Malonic Acid SCHEMBL15323198 | 0.77 | GPR84 (0.41) | OR51E2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2836833-A1 | PRENATAL SCREENING FOR DOWN SYNDROME AND TRISOMY 18 | Wayne State University (US) | 2015-02-18 | — | — | EP | disclosed |
| WO-2013155456-A1 | PRENATAL SCREENING FOR DOWN SYNDROME AND TRISOMY 18 | WAYNE STATE UNIVERSITY (US) | 2013-10-17 | — | — | WO | disclosed |